A pilot prospective single-arm cohort study on the Effectiveness and Safety of Electroacupuncture at ST36(Zusanli) in Treating Primary Premature Ejaculation
This is a pilot prospective single-arm cohort study to verify the Effectiveness and Safety of Electroacupuncture at ST36(Zusanli) in Treating Primary Premature Ejaculation, based on the result on animal study that daily electroacupuncture at ST36(Zusanli) for 30 days could delay the ejaculation of male SD rats.
Study Type
INTERVENTIONAL
Allocation
NA
Purpose
TREATMENT
Masking
NONE
Enrollment
35
Electroacupuncture at ST36, which located at the anterior aspect of the lower leg, 3 cun below ST 35, one finger-breadth (middle finger) from the anterior crest of the tibia. Twice or 3 times per week, for 6 weeks.
Nanjing Drum Tower Hospital Affiliated to Nanjing University Medical School
Nanjing, Jiangsu, China
RECRUITINGChange from baseline intravaginal ejaculatory latency time
IELT
Time frame: Week 6, 10, 14, 18
Premature Ejaculation Diagnose Tool
The premature ejaculation diagnostic tool (PEDT) is a brief diagnostic measure to assess premature ejaculation
Time frame: Week 0, 6, 10, 14, 18
Premature Ejaculation Profile
Premature Ejaculation Profile (PEP) is a self-reported outcome instrument for evaluating domains of PE and its treatment and comprises of four single-item measures, a profile, and an index score.
Time frame: Week 0, 6, 10, 14, 18
Chinese Index of Premature Ejaculation
The Chinese Index of Premature Ejaculation(CIPE) has 10 questions, focusing on libido, erectile function, ejaculatory latency, sexual satisfaction and difficulty in delaying ejaculation, self-confidence and depression. Each question was responded to on a 5 point Likert-type scale.
Time frame: Week 0, 6, 10, 14, 18
Penile Nerve Electrophysiology
An electrophysiological technique used to examine the axonal composition and reflex activity of the penile nerve
Time frame: Week 0, 6, 18
Clinical Global Impression of Change
Clinical Global Impressions (CGI) scale is a well-established research rating tool applicable to all psychiatric disorders that can easily be used by the practicing clinician to meet this need.
Time frame: Week 6, 18
fMRI
Measure GABA levels in thalamic regions using GABA spectroscopy
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.
Time frame: Week 0, 6