Sarcopenia is characterized by loss of skeletal muscle mass and strength with advancing age. It is linked to an increased risk of falls, disability, length of hospitalization, poor quality of life, and burden of health care. Nutrition and physical activity are the major modifiable factors to prevent and mitigate sarcopenia. However, most studies focused on the explore the effects of physical activity or single nutrient supplementation. Whether a multi-intervention program combining protein-rich food intake, nutrition education, and exercise can more effectively reduce the risk of sarcopenia still needs to be explored at the community level. This study aimed to investigate the effects of a multi-intervention program (protein-rich food supplement, nutrition education, and exercise) on reducing the risk of sarcopenia. The primary outcome is to evaluate the effect of a multi-intervention program and exercise intervention only. The second outcome is to assess the impact of animal and plant source protein on muscle mass and physical performance. Investigators will recruit the study participants over the age of 60 from the free-living community. All participants were randomized into five groups: animal protein, plant protein, exercise and nutrition education, exercise alone, and control. For 8 weeks, except for control group, all four groups receive resistance training 3 times/week. However, the animal and plant protein groups provide milk 240 mL and soy milk 230 mL (7-8 g protein/serving) after exercise, respectively, and receive personal nutritional counseling and education to adhere to dietary recommendations. Dual-energy X-Ray using to evaluate the body composition and measure the grip strength, five-time chair stand test, and gait speed to assess physical performance pre- and post-intervention. The results of this study can be used to prevent muscle mass loss and frailty for older adults in the community.
Study Type
INTERVENTIONAL
Allocation
NON_RANDOMIZED
Purpose
PREVENTION
Masking
NONE
Enrollment
86
This study aimed to investigate the effects of a multi-intervention program (protein-rich food supplement, nutrition education, and exercise) on reducing the risk of sarcopenia.
Yi-Chen Huang
Taichung, Baseline and Post Test of Intervention, Taiwan
The effect of a multi-intervention program and exercise intervention on muscle mass
The changes from baseline in muscle mass will be assessed by DXA in kilogram/meter2.
Time frame: From the date of the first time to collect the baseline data until the date of completion of the study (after intervention), assessed up to 12 weeks
The effect of a multi-intervention program and exercise intervention on calf circumference
The changes from baseline in calf circumference will be assessed by tape in cm
Time frame: From the date of the first time to collect the baseline data until the date of completion of the study (after intervention), assessed up to 12 weeks
The effect of a multi-intervention program and exercise intervention on grip strength
The changes from baseline in grip strength will be assessed by grip meter in kg
Time frame: From the date of the first time to collect the baseline data until the date of completion of the study (after intervention), assessed up to 12 weeks
The effect of a multi-intervention program and exercise intervention on walking speed
The changes from baseline in walking speed will be assessed by timer in meters/second
Time frame: From the date of the first time to collect the baseline data until the date of completion of the study (after intervention), assessed up to 12 weeks
The effect of a multi-intervention program and exercise intervention on sit-to-stand speed
The changes from baseline in sit-to-stand test will be assessed by timer in second
Time frame: From the date of the first time to collect the baseline data until the date of completion of the study (after intervention), assessed up to 12 weeks
The effect of a multi-intervention program and exercise intervention on dietary intake
The changes from baseline in dietary intake at 8 weeks will be assessed by questionnaire.
Time frame: From the date of the first time to collect the baseline data until the date of completion of the study (after intervention), assessed up to 12 weeks
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