a randomized clinical trial to compare the effect of twice weekly versus daily iron therapy in treating anemia in children with cerebral palsy, to be conducted at Department of pediatric medicine children's hospital PIMS islamabad.
a total of 160 children of either gender with age between 6 and 60 months diagnosed with cerebral palsy and concomitant iron deficiency anemia will be enrolled, they will be allocated two groups by lottery method. one group will be given ferrous sulphate 3mg/kg daily in the form of syrup and other group will be given ferrous sulphate 3mg/kg twice weekly in the form of syrup for a period of 4 weeks. the primary outcome will be measured as rise in hemoglobin levels more than or equal to 1g/dl at 4 weeks.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Enrollment
160
ferrous sulphate oral in the form of syrup
Change in Hemoglobin levels from baseline
rise in Hb at the end of 4 weeks as more than equal to 1g/dl
Time frame: 4 weeks
Mean change in MCV (Mean Corpuscular Volume)
mean change from baseline at the end of 4 weeks
Time frame: 4 weeks
Mean change in mean corpuscular hemoglobin concentration (MCHC)
mean change from baseline at the end of 4 weeks
Time frame: 4 weeks
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.