Hyaluronic Acid Gel in Ridge Preservation

Ain Shams University24 enrolled

Overview

hyaluronic acid gel applied at the extraction socket after extraction immediately to preserve the socket from post extraction resorption. hyaluronic acid has ability for osteogenesis and new bone formation.

twenty-four patients with one hopeless tooth at least, first CBCt before extraction to evaluate the dimension of the socket, then atraumatic extraction of the tooth to preserve the bony wall of the socket, after extraction and curettage the socket applied hyaluronic acid gel inside the socket and applied collagen membrane to secure the socket. After 4 months of extraction, CBCt was done to evaluate the dimension of the socket and the effect of hyaluronic acid. Furthermore, The core biopsy was taken by trephine bur at the time of implant placement for evaluate the histological appearance of the bone to evaluate the secondary outcome. then after three months the crown was delivered as a prosthetic part.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

SINGLE

Enrollment

Conditions

Hyaluronic Acid Gel for Preservation the Extraction Socket

Interventions

Hyaluronic acidDRUG

Alveolar ridge preservation by atraumatic tooth extraction and socket curettage then application hyaluronic acid gel after extraction and covering the socket by collagen membrane.

empty socketOTHER

Alveolar ridge preservation by atraumatic tooth socket without application any drug but just covering the socket by collagen membrane.

Eligibility

Sex: ALLMin age: 20 YearsMax age: 50 Years

Medical Language ↔ Plain English

Inclusion Criteria: 1. Healthy adult patients as evidenced by Burkett's oral medicine health history questionnaire 2. Both genders. 3. Age from 20 -50 years old. 4. Having at least one hopeless teeth indicated for extraction. 5. Esthetic zone teeth (anterior or premolar). 6. Sockets type 1 or 2 . 7. Patient should agree to sign a written consent after the nature of the study will be explained. \- Exclusion Criteria: 1- Smokers. 2- Pregnant and breast-feeding females. 3- Mentally retarded Patients. 4- Prisoners and handicapped patients. 5- Patients with malocclusion. \-

Locations (1)

Ain shams University

Cairo, Egypt

Outcomes

Primary Outcomes

clinical outcome

measurement clinical bone width of the socket by millimeter before and 4 months after extraction ...

Time frame: baseline(before extraction)/ four months later after extraction

Radiographic measurement

Radiographic measurement of bone width by CBCt before and 4 months after extraction

Time frame: baseline(before extraction)/ four months later after extraction

Radiographic measurement

Radiographic measurement of bone height by CBCt before and 4 months after extraction.

Time frame: baseline (before extraction)/ four months later after extraction

Secondary Outcomes

histological analysis

The bone biopsy will be taken by trephine bur. And evaluate bone quality.

Time frame: after 4 months of extraction at the time of implant placement.

histomorphometric analysis

The bone biopsy will be taken by trephine bur. And evaluate bone quantity.

Time frame: after 4 months of extraction at the time of implant placement.

Data from ClinicalTrials.gov

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