This study is intended to evaluate how significantly a proprietary curcumin formulation (curQ+® or liposomal curcumin) results in greater GI absorption compared to 95% curcumin extract over a 6-hour time period following a single oral dose in healthy men \& women.
This study is intended to evaluate how significantly a proprietary curcumin formulation (curQ+® or liposomal curcumin) results in greater GI absorption compared to 95% curcumin extract over a 6-hour time period following a single oral dose in healthy men \& women. Absorption enhancement will be based upon producing the greatest plasma curcumin concentration (AUC). Secondarily, this study is intended to evaluate the safety and tolerability of the curQ+® \& liposomal curcumin formulations.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
NONE
Enrollment
25
95% curcumin extract powder
curQ+ curcumin formulation
liquid liposomal curcumin formulation
University of Texas Health Center
Houston, Texas, United States
Absorption of curcumin as measured in serum via Liquid Chromatography Tandem Mass Spectrometry (LC/MS/MS)
The difference between the absorption of curcumin from the formulations curQ+ or liposomal curcumin versus 95% curcumin powder as measured in serum via Liquid Chromatography Tandem Mass Spectrometry (LC/MS/MS)
Time frame: 6 hours
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