Introduction: As conventional treatments for overactive bladder (OAB) have not yet shown satisfactory results, new approaches are needed. Therefore, this study aimed to investigate the efficacy and safety of acupuncture combined with mirabegron for the treatment of OAB. Methods: This prospective cohort study enrolled 80 OAB patients who were then divided into control and treatment groups using a randomized number-table method. The control group was administered mirabegron alone (50 mg/day), while the treatment group was administered mirabegron orally along with acupuncture at the following points: guanyuan (CV4), zhongji (CV3), and sanyinjiao (SP6). The OAB symptom score (overactive bladder syndrome score \[OABSS\]), voiding, urgency, nocturia, incontinence, and incidence of related adverse events were compared between the two groups at baseline and after 4, 8, and 12 weeks of treatment.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
QUADRUPLE
Enrollment
75
Patients in the control group were treated with 50 mg of mirabegron (Astellas Pharma, Tokyo, Japan) for 12 weeks.
Patients in the treatment group were treated with acupuncture combined with mirabegron.
Ganzhou People's Hospital
Ganzhou, Jiangxi, China
Overactive bladder syndrome scores (OABSS)
overactive bladder syndrome scores of patient
Time frame: 4, 8, and 12 weeks after treatment
voiding diary indicators (voiding, urgency, nocturia, and incontinence)
Number of voiding, urgency, nocturia, and incontinence in one day
Time frame: 4, 8, and 12 weeks after treatment
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