Patients undergone total knee replacement are randomized to receive a "fast track" regional anesthesia protocol or a "traditional" regional anesthesia continuous infusion by both a femoral and sciatic catheter to assess if this latter technique may reduce persistent postoperative pain six months after surgery
Patients undergone to primary total knee replacement with spinal anesthesia are randomized to receive a continuous adductor canal block infusion + an ipack block or a continuous femoral nerve block + a continuous sciatic nerve block just at the end of surgery. Both group will receive a multimodal analgesia with paracetamol, ketorolac, desametasone and morphine as a rescue.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
NONE
Enrollment
436
continuous regional anesthesia in total knee replacement
Policlinico di Monza SPA
Monza, Monza Brianza, Italy
RECRUITINGPersistent post surgical pain
Numeric rating score (0-10) over 4 at the follow up 6-month after total knee replacement
Time frame: 0-6-month
acute postoperative pain
Numeric rating score (0-10) over 4 in POD0, POD1, POD2, POD3
Time frame: 0-72 hours
Morphine requirement
total morphine administration via PCA in POD0, POD1, POD2, POD3
Time frame: 0-72 hours
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