The goal of this observational, quality improvement study is to compare the effect of a dose of morphine given during gall-bladder removal surgery. The main questions to answer are: * Do participants, who are given given a dose of morphine during gall-bladder removal surgery, experience less pain after surgery? * Does a dose of morphine during gall-bladder removal surgery cause more side effects? The investigators will compare the effects of two types of anesthesia: a) anesthesia without morphine during surgery, and b) anesthesia with morphine during surgery.
The investigators will use Redcap secure web application (via Open Patient Data Explorative Network, a subsidiary under University Hospital of Odense, Denmark) for data collection and data management. No sample size has been collected as per the observational design. The investigators expect to include an equal number in each study arm, as there has been no indication of change in indications for surgery type. The investigators expect to use students T-test for comparison of groups. If possible logistic regression analyses will be undertaken.
Study Type
OBSERVATIONAL
Enrollment
300
Morphine dose = 0,1 mg mg/kg (maximum 10 mg) intravenous given 20 min after start of surgery
Hospital of south West Jutland
Esbjerg, Denmark
RECRUITINGUse of rescue analgesia.
Calculated as morphine equivalents.
Time frame: 24 hours
Intraoperative opioid use.
Calculated as morphine equivalents.
Time frame: 24 hours
Pain-score at arrival in postoperative ward.
Intervals: 0 = no pain, 1 = light pain (equivalent to numerical ranking scale (NRS) 1-3), 2 = moderate pain (equivalent to NRS 4-6), 3 = severe pain (equivalent to NRS 7-10).
Time frame: 24 hours
Pain-score at discharge from postoperative ward.
Intervals: 0 = no pain, 1 = light pain (equivalent to NRS 1-3), 2 = moderate pain (equivalent to NRS 4-6), 3 = severe pain (equivalent to NRS 7-10).
Time frame: 24 hours
Rescue antiemetic treatment in postoperative ward.
Antiemetic drugs and doses registered.
Time frame: Up to 24 hours follow up.
Time in postoperative ward.
Minutes.
Time frame: 24 hours
Analgesic treatment in surgical ward if admitted
Only if admitted (a large proportion of patients expected to undergo out-patient procedure). Calculated as morphine equivalents.
Time frame: 24 hours
Antiemetic treatment in surgical ward.
Only if admitted (a large proportion of patients are expected to undergo out-patient procedure). Antiemetic drugs and doses registered.
Time frame: 24 hours
Hospital length of stay.
Only if admitted (a large proportion of patients are expected to undergo out-patient procedure).
Time frame: 1 month
Emergence from anesthesia.
Surrogate measure of emergence from anesthesia time.
Time frame: 24 hours
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