This was a retrospective, observational cohort study. Data were analyzed from the Intelligent Research in Sight (IRIS) registry from October 8, 2019, through November 26, 2021, with a follow-up period of 12 months following the first brolucizumab injection (index date).
Study Type
OBSERVATIONAL
Enrollment
2,079
Novartis
East Hanover, New Jersey, United States
Change in Best Recorded Visual Acuity, Stratified by Prior Treatment Status
Time frame: Baseline up to 12 months
Change in Injection Interval at 12 Months of Brolucizumab Treatment Compared with Prior Anti-vascular Endothelial Growth Factor (VEGF) Treatment
Time frame: Baseline up to 12 months
Number of eyes with adverse events
Time frame: Baseline up to 12 months
Time to adverse event
Time frame: Baseline up to 12 months
Number of brolucizumab injections prior to adverse event
Time frame: Baseline up to 12 months
Brolucizumab Injection Interval and Interval Extension, Stratified by Pre-Switch Interval
Time frame: Baseline up to 12 months
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