The Effect of Aspirin on Recurrent Acute Pancreatitis

Inclusion Criteria: * Patients with with recurrent acute pancreatitis Exclusion Criteria: * Less than 2 episodes of acute pancreatitis in the past year * Latrogenic AP (pancreatitis due to endoscopic retrograde cholangiopancreatography, surgery, or after other invasive treatment). Iatrogenic pancreatitis will not count as an episode of recurrent pancreatitis * Previous allergy to Non-Steroid Anti-inflammatory Drugs (NSAIDs) * Regularly taking aspirin or other NSAIDs \>3 doses per week * Contradictions for the medications of NSAIDs, including Active peptic ulcer disease or gastrointestinal hemorrhage within 3 months or previous peptic ulcer, history of significant hepatic or renal disease, platelet count less than 100X10\^9/L or international normalized ratio (INR) \>1.5) * Biliary stones * Receiving endoscopic sphincterotomy and/or pancreatic stent placement and/or cholecystectomy and/or pancreatic surgery after the latest pancreatitis or planning to undergo one of those interventions within preceding 2 years * Patients with the level of serum triglycerides of \>5.65 mmol/L and did not receive regular lipid-lowering therapy * Primary hyperparathyroidism has been well-treated after last episode of pancreatitis and recruitment or will be operated in \<2 years * Patients with previously heavy alcohol consumption (50g/day for men, 40g/day for women) and have not quit drinking, or have significant withdrawal symptoms * Pregnant or breastfeeding patients * Inability to give informed consents