The purpose of this study is to observe whether there are differences in adipokines in the aqueous humor between patients with primary open-angle glaucoma (POAG) and healthy controls
1\. Inclusion criteria: Patients aged 18 years or older, diagnosed with primary open-angle glaucoma (POAG) and healthy controls (who underwent cataract surgery). 2\. Exclusion criteria: 1. Other Ocular Diseases: Patients with concurrent ocular diseases such as macular degeneration, retinal detachment, etc., are excluded. 2. Ocular Surgery History: individuals who have undergone intraocular or laser surgery within the past 6 months, except for uncomplicated cataract surgery. 3. History of Ocular Trauma or Inflammation 4. Systemic Diseases or Mental Disorders: Patients with systemic diseases(e.g., diabetes, rheumatoid arthritis) and those with mental disorders are excluded. 5. Pregnancy or Lactation: Females who are pregnant or lactating are excluded. 6. Presence of any retinal or optic nerve disease other than glaucoma.
Study Type
OBSERVATIONAL
Enrollment
2
This study has no intervention
Peking University Third Hosipital
Beijing, Beijing Municipality, China
RECRUITINGConcentration of adipokines in aqueous humor
Aqueous humor samples were assessed for adipokines and inflammatory cytokines by Luminex bead-based multiplex array
Time frame: Cross-sectional baseline
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