The purpose of the study is to assess whether infection rate is reduced with use of antibiotic-coated plate in severe open tibial fractures compare to use of external fixators
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
NONE
Enrollment
178
A plate for fixing long bone fractures is coated with antibiotics cement prepared in theatre
external fixators are applied to participants with severe long bone fractures
Federal Medical Centre, Owo
Owo, Ondo State, Nigeria
Univeristy College Hospital, Ibadan, Nigeria
Ibadan, Oyo State, Nigeria
number of participants with fracture-related infection after 1 year
participants will be followed-up for one year and occurrence of infection at any point during this time period will be noted and recorded once
Time frame: one year
number of participants who have fracture union after one year
participants will be assessed clinically and radiologically at 3months, 6months, and one year
Time frame: one year
number of participants who require re-operation after one year
during the course of follow-up, Patients with infection or other complications like malunion or non-union who require surgical intervention to achieve union will be noted and recorded
Time frame: one year
change in 12-item Short Form Survey (SF-12) score at baseline and at one year follow-up
SF-12 score of participants will be taking at baseline and also at one year of follow-up and these two scores will be assessed to determine any differences
Time frame: one year
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