Multi-center Clinical Observation and Mechanism Study of Yunnan Baiyao in Different Stages of Diabetic Foot Ulcer

Inclusion Criteria: 1. The age of the subjects is 18-80 years old; 2. Diagnose diabetes according to WHO standards; 3. Diagnosis of Diabetic foot; 4. Confirmed as one of the stages of infection progression and granulation growth; 5. Voluntarily participate in this study and sign an informed consent form. Exclusion Criteria: 1. Severe diseases such as acute myocardial infarction, heart failure, hepatitis, shock, and respiratory failure have not been corrected yet; 2. Blood glucose is out of control, Glucose test#Fasting blood sugar\>15mmol /L, Glycated hemoglobin\>12%; 3. There is active bleeding inside the wound, and routine basic treatment plans cannot be implemented; 4. Serum albumin\<20g/L; Hemoglobin\<60g/L; Platelets\<50 × 109/L; 5. Late stage subjects with malignant tumors; 6. Active period of autoimmune diseases; 7. Have a history of allergy to Yunnan Baiyao; 8. The subject is unable to cooperate or has mental disorders; 9. According to the judgment of the researcher, the subject has a clear reason that cannot be removed and affects wound healing, which is not suitable for this study or cannot comply with the requirements of this study.