Waldenström macroglobulinemia (WM) is an incurable disease. BCL2 antagonist, an important anti-apoptosys molecule, is already approved for the treatment of chronic lymphocytic leukemia (CLL) and acute myeloid leukemia. Recently, a clinical trial including 32 patients with WM treated with Venetoclax showed an overall response rates of 84% and a major response rate of 81%. However, there is no in real life data, in the french population, of the efficiency of Venetoclax in WM. The aim of our multicentric retrospective study is to evaluate the efficiency and tolerance of Venetoclax in WM.
Study Type
OBSERVATIONAL
Enrollment
45
Observational study
CHU Poitiers
Poitiers, France
RECRUITINGEfficiency
ORR, MRR
Time frame: 2018 to 2025
Tolerance
Adverse events
Time frame: 2018 to 2025
Efficiency in specific population
ORR in CXCR4 mutated patients, ORR in patients previously treated with BTK inhibitors
Time frame: 2018 to 2025
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.