Study of Adaptive Radiotherapy for High-grade Glioma Based on Interfraction MRI

Inclusion Criteria: 1. Age ≥18 years old; 2. High-grade glioma was confirmed by pathology after surgery; 3. ECOG score 0-2 points; 4. Receiving the standard STUPP regimen (i.e. 6 weeks of temozolomide concurrent chemoradiotherapy +6 cycles of temozolomide adjuvant chemotherapy); 5. Baseline data available. Exclusion Criteria: 1. The pathological diagnosis is not clear; 2. No synchronous chemotherapy/adjuvant chemotherapy \< 6 cycles; 3. There are other malignant tumors; 4. Previously radiotherapy to the head; 5. Interruption of radiotherapy for more than 5 days; 6. Failure to collect baseline data.