Cardiac amyloidosis (CA) has recently been reported as a common cause of heart failure with preserved left ventricular ejection fraction (HFpEF), with a prevalence of 6% in elderly HFpEF patients. However, the diagnosis of CA is still challenging and requires multiple costly investigations. Regardless of the type of CA, TTR or AL, early diagnosis significantly improves prognosis. In this study, the investigators aimed to determine the prevalence of CA in Tunisian HFpEF patients and to identify clinical and ultrasound criteria predictive of CA.
Study Type
OBSERVATIONAL
Enrollment
87
Security Hospital Forces
La Marsa, Tunis Governorate, Tunisia
Prevalence of cardiac amyloidosis among HFpEF old Tunisian Patients
Prevalence of cardiac amyloidosis in a Tunisian cohort of HFpEF patients aged 60 years or older with interventricular septal thickness equal to or greater than 12 mm
Time frame: one year
Identify imaging criteria predictive of cardiac amyloidosis on CMR and echocardiography
Number of cardiac amyloidosis patients with impaired global longitudinal left ventricular strain and/or impaired left atrial strain on echocardiography and/or elevated extra cellular volume (ECV) on CMR.
Time frame: one year
Frequency of different types of cardiac amyloidosis
Time frame: one year
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