A Retrospective Study on the Treatment of Intermediate and Advanced Liver Cancer.

Inclusion Criteria: * ≥18 years old, both men and women * primary liver cancer confirmed by liver biopsy or history of hepatitis B, AFP, and typical imaging findings * patients with liver function Child-Pugh A or B (≤8 points) * BCLC stage B and stage C * expected survival time ≥8 weeks * patients with generally good performance status (ECOG PS score 0 or 1) Exclusion Criteria: * The patient's key data is missing * liver metastatic cancer confirmed by histology or cytology * patients who interrupt treatment due to intolerance of adverse drug reactions * combined with primary malignant tumors of other organs within 5 years; combined with other serious diseases, such as severe heart disease, renal insufficiency, severe infection, bleeding, etc. * combined with systemic infection, autoimmune disease, or other types of tumors; previous allogeneic bone marrow transplantation or solid organ transplantation * study participants known to have mental illness * situations such as drug use or substance abuse