Autonomic Dysreflexia in Spinal Cord Injuries: UDS Filling Speed Impact

Pusan National University Yangsan Hospital30 enrolled

Overview

In patients with spinal cord injury, the investigators want to understand and understand the differences in AD prevalence and characteristics according to bladder injection rate, and to determine which factors have a greater influence between bladder expansion or injection rate.

It has been reported that there is a difference in the degree of AD between the bladder and urinary tract motility tests, suggesting a potential difference according to the injection rate. According to Liu et al., the authors noted that stimulation of the urethra, prostate, and internal sphincter appears to induce AD more strongly than the injection rate. In addition, the two main factors contributing to AD among urinary kinetics tests are the patient's age and bladder maximum urination pressure. Considering these factors is important in preventing AD during urinary kinetics tests. Despite these previous studies, the prevalence and severity of AD according to the injection rate of urinary kinetics tests in SCI have not been quantitatively evaluated.

Study Type

OBSERVATIONAL

Enrollment

Conditions

Spinal Cord Injuries Autonomic Dysreflexia UDS Filling Speed

Interventions

Urodynamic testOTHER

Urodynamic testing is performed using saline solution at the same temperature as body temperature (37 degrees) at two injection speeds of 10 mL/min and 100 mL/min, respectively.

Eligibility

Sex: ALL

Medical Language ↔ Plain English

Inclusion Criteria: 1. Patients with chronic spinal cord injury 6 months after receiving the award 2. Patients with confirmed AD due to bladder fullness in previous urodynamic test 3. Patients confirmed to have neurological damage level C1-T6, AIS A or B Exclusion Criteria: 1. Patients who cannot perform the test because their systolic blood pressure remains at 150 mmHg during the urodynamic test 2. Patients who cannot undergo testing due to hemodynamic instability 3. Patients who cannot undergo testing due to overt urinary tract infection

Locations (1)

Pusan National University Yangsan Hospital

Yangsan, Gyeongsangnam-do, South Korea

RECRUITING