Serpin C and Soluble Fms-like Tyrosine Kinase-1 Levels in Normotensive Pregnant Women May Predict the Development of Preeclampsia

Benha University60 enrolled

Overview

Evaluation of the predictability of estimated levels of Serpin C, sFlt-1 and placental growth factor (PLGF) in blood samples obtained during the 1st trimester from normotensive pregnant women for identification of women liable to develop PE during the course of pregnancy.

Study Type

OBSERVATIONAL

Enrollment

Conditions

Pre-Eclampsia

Interventions

ELISADIAGNOSTIC_TEST

ELISA estimation of PLGF, sFlt-1 and Serpin C

Eligibility

Sex: FEMALEMin age: 25 YearsMax age: 45 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * Normotensive pregnant women had singleton fetus presenting during the 1st trimester * free of exclusion criteria Exclusion Criteria: * Age * Sex * Hypertension

Locations (1)

Banha University

Banhā, El- Qalyobia, Egypt

Outcomes

Primary Outcomes

Role of Biomarkers in detection of GHTN

The predictability of serum biomarkers' levels estimated at enrolment for the development of GHTN.

Time frame: 9 months

Data from ClinicalTrials.gov

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