Melatonin is a hormone naturally found in our body that increases in our blood at night and controls how we sleep. Melatonin can also be taken as a pill and numerous clinical trials have documented improved sleep quality following melatonin supplementation before bed. However, it is not known whether such supplements actually increase blood melatonin above normal levels, particularly at night. The aims of this study are to investigate whether a novel melatonin supplement (Ritual Sleep BioSeriesTM Melatonin) can increase blood melatonin in human participants at night, and to determine if taking the supplement before bed for two-weeks can improve sleep quality.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
QUADRUPLE
Enrollment
15
5mg melatonin supplement, once daily, from Ritual BioSeries
Placebo supplement, once daily, from Ritual BioSeries
Sport & Health Sciences University of Exeter
Exeter, Devon, United Kingdom
Pharmacokinetic
Serum melatonin concentration area under curve
Time frame: 10 hours
Sleep efficiency
Sleep efficiency, as total time asleep as percentage of time in bed
Time frame: 2 weeks
Sleep diary
Sleep diary recorded daily via 'consensus sleep diary - core'
Time frame: 2 weeks
Recovery and well being
Recovery and well being recorded via recovery stress questionnaire (REST-Q)
Time frame: 2 weeks
Sleep quality
Sleep quality determined via 'Pittsburgh Sleep Quality Index survey'
Time frame: 2 weeks
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