This study will enroll stroke patients and healthy participants. Participants will complete baseline measures followed by a music playing task during fMRI and simultaneous measurement of motor response using electromyography (EMG) and accelerometry and affective response using electrodermal activity (EDA) and self-reports. The music task consists of tapping an MRI-compatible MIDI drum with either: (1) improvisation or maintaining the beat and (2) live or recorded piano accompaniment. The primary objectives are to identify the motor, affective, and neural outcomes of improvisation and live accompaniment in music playing tasks.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
OTHER
Masking
NONE
Enrollment
26
For the music playing task, participants will tap on an MRI compatible MIDI drum in response to music, while following directions to either (1) maintain the beat of the music or (2) improvise a beat along with the music. Piano accompaniment for drum playing will be provided either (1) with a recording or (2) by a live music therapist. Participants will complete all four combinations of these music playing tasks following the sequence of experimental order 3. Each of the four tasks will be repeated with four one-minute songs, resulting in a total of 16 minutes of drum playing required to complete the study procedures. Participants will repeat the same task order with each song to facilitate task comprehension and task completion accuracy. Song order will be randomized for all participants.
NYU Langone Health
New York, New York, United States
Total Acceleration of Hand Movements during Improvisation + Live Accompaniment Task
This measurement will be taken using an MRI-compatible accelerometer attached to the hand with a Velcro strap.
Time frame: Day 1 (About 3 hours)
Total Acceleration of Hand Movements during Improvisation + No Live Accompaniment Task
This measurement will be taken using an MRI-compatible accelerometer attached to the hand with a Velcro strap.
Time frame: Day 1 (About 3 hours)
Total Acceleration of Hand Movements during No Improvisation + No Live Accompaniment Task
This measurement will be taken using an MRI-compatible accelerometer attached to the hand with a Velcro strap.
Time frame: Day 1 (About 3 hours)
Total Acceleration of Hand Movements during No Improvisation + Live Accompaniment Task
This measurement will be taken using an MRI-compatible accelerometer attached to the hand with a Velcro strap.
Time frame: Day 1 (About 3 hours)
Total Muscle Activation during Improvisation + Live Accompaniment Task
This measurement will be taken using MRI-compatible electromyography sensors placed on the arm.
Time frame: Day 1 (About 3 hours)
Total Muscle Activation during Improvisation + No Live Accompaniment Task
This measurement will be taken using MRI-compatible electromyography sensors placed on the arm.
Time frame: Day 1 (About 3 hours)
Total Muscle Activation during No Improvisation + No Live Accompaniment Task
This measurement will be taken using MRI-compatible electromyography sensors placed on the arm.
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Time frame: Day 1 (About 3 hours)
Total Muscle Activation during No Improvisation + Live Accompaniment Task
This measurement will be taken using MRI-compatible electromyography sensors placed on the arm.
Time frame: Day 1 (About 3 hours)
Neural Activation in Primary Motor Cortex during Improvisation + Live Accompaniment Task
Measured using functional MRI (fMRI). Summary beta values representing the level of brain activity will be calculated.
Time frame: Day 1 (About 3 hours)
Neural Activation in Primary Motor Cortex during Improvisation + No Live Accompaniment Task
Measured using functional MRI (fMRI). Summary beta values representing the level of brain activity will be calculated.
Time frame: Day 1 (About 3 hours)
Neural Activation in Primary Motor Cortex during No Improvisation + No Live Accompaniment Task
Measured using functional MRI (fMRI). Summary beta values representing the level of brain activity will be calculated.
Time frame: Day 1 (About 3 hours)
Neural Activation in Primary Motor Cortex during No Improvisation + Live Accompaniment Task
Measured using functional MRI (fMRI). Summary beta values representing the level of brain activity will be calculated.
Time frame: Day 1 (About 3 hours)
Neural Activation in Supplementary Motor Cortex during Improvisation + Live Accompaniment Task
Measured using functional MRI (fMRI). Summary beta values representing the level of brain activity will be calculated.
Time frame: Day 1 (About 3 hours)
Neural Activation in Supplementary Motor Cortex during Improvisation + No Live Accompaniment Task
Measured using functional MRI (fMRI). Summary beta values representing the level of brain activity will be calculated.
Time frame: Day 1 (About 3 hours)
Neural Activation in Supplementary Motor Cortex during No Improvisation + No Live Accompaniment Task
Measured using functional MRI (fMRI). Summary beta values representing the level of brain activity will be calculated.
Time frame: Day 1 (About 3 hours)
Neural Activation in Supplementary Motor Cortex during No Improvisation + Live Accompaniment Task
Measured using functional MRI (fMRI). Summary beta values representing the level of brain activity will be calculated.
Time frame: Day 1 (About 3 hours)
Electrodermal Activity (EDA) during Improvisation + Live Accompaniment Task
EDA is a procedure for measuring emotional excitement by recording the skin's natural electrical activity. The measurements will be taken using two MRI-compatible sensors attached to the palm of the hand.
Time frame: Day 1 (About 3 hours)
Electrodermal Activity (EDA) during Improvisation + No Live Accompaniment Task
EDA is a procedure for measuring emotional excitement by recording the skin's natural electrical activity. The measurements will be taken using two MRI-compatible sensors attached to the palm of the hand.
Time frame: Day 1 (About 3 hours)
Electrodermal Activity (EDA) during No Improvisation + No Live Accompaniment Task
EDA is a procedure for measuring emotional excitement by recording the skin's natural electrical activity. The measurements will be taken using two MRI-compatible sensors attached to the palm of the hand.
Time frame: Day 1 (About 3 hours)
Electrodermal Activity (EDA) during No Improvisation + Live Accompaniment Task
EDA is a procedure for measuring emotional excitement by recording the skin's natural electrical activity. The measurements will be taken using two MRI-compatible sensors attached to the palm of the hand.
Time frame: Day 1 (About 3 hours)
Music Playing Self-Report Questionnaire - Pleasure Score during Improvisation + Live Accompaniment Task
The questionnaire includes 1 question measuring participant's pleasure while performing the music activity. The item is rated on a Likert scale from 1 (low) to 5 (high); higher scores indicate greater pleasure.
Time frame: Day 1 (About 3 hours)
Music Playing Self-Report Questionnaire - Pleasure Score during Improvisation + No Live Accompaniment Task
The questionnaire includes 1 question measuring participant's pleasure while performing the music activity. The item is rated on a Likert scale from 1 (low) to 5 (high); higher scores indicate greater pleasure.
Time frame: Day 1 (About 3 hours)
Music Playing Self-Report Questionnaire - Pleasure Score during No Improvisation + No Live Accompaniment Task
The questionnaire includes 1 question measuring participant's pleasure while performing the music activity. The item is rated on a Likert scale from 1 (low) to 5 (high); higher scores indicate greater pleasure.
Time frame: Day 1 (About 3 hours)
Music Playing Self-Report Questionnaire - Pleasure Score during No Improvisation + Live Accompaniment Task
The questionnaire includes 1 question measuring participant's pleasure while performing the music activity. The item is rated on a Likert scale from 1 (low) to 5 (high); higher scores indicate greater pleasure.
Time frame: Day 1 (About 3 hours)
Music Playing Self-Report Questionnaire - Cognitive Challenge Score during Improvisation + Live Accompaniment Task
The questionnaire includes 1 question measuring participant's cognitive challenge while performing the music activity. The item is rated on a Likert scale from 1 (low) to 5 (high); higher scores indicate greater cognitive challenge.
Time frame: Day 1 (About 3 hours)
Music Playing Self-Report Questionnaire - Cognitive Challenge Score during Improvisation + No Live Accompaniment Task
The questionnaire includes 1 question measuring participant's cognitive challenge while performing the music activity. The item is rated on a Likert scale from 1 (low) to 5 (high); higher scores indicate greater cognitive challenge.
Time frame: Day 1 (About 3 hours)
Music Playing Self-Report Questionnaire - Cognitive Challenge Score during No Improvisation + No Live Accompaniment Task
The questionnaire includes 1 question measuring participant's cognitive challenge while performing the music activity. The item is rated on a Likert scale from 1 (low) to 5 (high); higher scores indicate greater cognitive challenge.
Time frame: Day 1 (About 3 hours)
Music Playing Self-Report Questionnaire - Cognitive Challenge Score during No Improvisation + Live Accompaniment Task
The questionnaire includes 1 question measuring participant's cognitive challenge while performing the music activity. The item is rated on a Likert scale from 1 (low) to 5 (high); higher scores indicate greater cognitive challenge.
Time frame: Day 1 (About 3 hours)
Neural Activation in Amygdala during Improvisation + Live Accompaniment Task
Measured using functional MRI (fMRI).
Time frame: Day 1 (About 3 hours)
Neural Activation in Amygdala during Improvisation + No Live Accompaniment Task
Measured using functional MRI (fMRI).
Time frame: Day 1 (About 3 hours)
Neural Activation in Amygdala during No Improvisation + No Live Accompaniment Task
Measured using functional MRI (fMRI).
Time frame: Day 1 (About 3 hours)
Neural Activation in Amygdala during No Improvisation + Live Accompaniment Task
Measured using functional MRI (fMRI).
Time frame: Day 1 (About 3 hours)
Neural Activation in Ventromedial Prefrontal Cortex during Improvisation + Live Accompaniment Task
Measured using functional MRI (fMRI).
Time frame: Day 1 (About 3 hours)
Neural Activation in Ventromedial Prefrontal Cortex during Improvisation + No Live Accompaniment Task
Measured using functional MRI (fMRI).
Time frame: Day 1 (About 3 hours)
Neural Activation in Ventromedial Prefrontal Cortex during No Improvisation + No Live Accompaniment Task
Measured using functional MRI (fMRI).
Time frame: Day 1 (About 3 hours)
Neural Activation in Ventromedial Prefrontal Cortex during No Improvisation + Live Accompaniment Task
Measured using functional MRI (fMRI).
Time frame: Day 1 (About 3 hours)
Neural Activation in Ventral Striatum during Improvisation + Live Accompaniment Task
Measured using functional MRI (fMRI).
Time frame: Day 1 (About 3 hours)
Neural Activation in Ventral Striatum during Improvisation + No Live Accompaniment Task
Measured using functional MRI (fMRI).
Time frame: Day 1 (About 3 hours)
Neural Activation in Ventral Striatum during No Improvisation + No Live Accompaniment Task
Measured using functional MRI (fMRI).
Time frame: Day 1 (About 3 hours)
Neural Activation in Ventral Striatum during No Improvisation + Live Accompaniment Task
Measured using functional MRI (fMRI).
Time frame: Day 1 (About 3 hours)
Neural Activation in Dorsolateral Prefrontal Cortex during Improvisation + Live Accompaniment Task
Measured using functional MRI (fMRI).
Time frame: Day 1 (About 3 hours)
Neural Activation in Dorsolateral Prefrontal Cortex during Improvisation + No Live Accompaniment Task
Measured using functional MRI (fMRI).
Time frame: Day 1 (About 3 hours)
Neural Activation in Dorsolateral Prefrontal Cortex during No Improvisation + No Live Accompaniment Task
Measured using functional MRI (fMRI).
Time frame: Day 1 (About 3 hours)
Neural Activation in Dorsolateral Prefrontal Cortex during No Improvisation + Live Accompaniment Task
Measured using functional MRI (fMRI).
Time frame: Day 1 (About 3 hours)
Functional Connectivity with the Ventral Striatum during Improvisation + Live Accompaniment Task
Measured using functional MRI (fMRI). Psychophysiological interactions (PPI) analysis will be used with the seed in the ventral striatum.
Time frame: Day 1 (About 3 hours)
Functional Connectivity with the Ventral Striatum during Improvisation + No Live Accompaniment Task
Measured using functional MRI (fMRI). Psychophysiological interactions (PPI) analysis will be used with the seed in the ventral striatum.
Time frame: Day 1 (About 3 hours)
Functional Connectivity with the Ventral Striatum during No Improvisation + No Live Accompaniment Task
Measured using functional MRI (fMRI). Psychophysiological interactions (PPI) analysis will be used with the seed in the ventral striatum.
Time frame: Day 1 (About 3 hours)
Functional Connectivity with the Ventral Striatum during No Improvisation + Live Accompaniment Task
Measured using functional MRI (fMRI). Psychophysiological interactions (PPI) analysis will be used with the seed in the ventral striatum.
Time frame: Day 1 (About 3 hours)