Obesity and lack of exercise are one of the reasons for high blood pressure. Exercise can reduce the risk of cardiovascular events by reducing weight and blood pressure. The precise formulation of exercise prescription by cardiopulmonary exercise test (CPET) can effectively control hypertension. Our research group has formulated 50 "exercise prescriptions for hypertension population" in the early stage, but how to further effectively implement them needs to be discussed. Based on the previous experience of undertaking the project "Exercise Prescription for Hypertensive People" of General Administration of Sport of the People's Republic of China, this research group discussed the important role of intelligent information management in the clinical effect evaluation and effective implementation of exercise prescription for hypertension; To explore the feasibility of making exercise prescription for hypertension based on 6-min walking test, and whether it is not inferior to or equivalent to the accuracy and effectiveness of making exercise prescription by CPET. The relevant results will lay a foundation for exploring the broader adaptation of hypertension exercise prescription to the population.
The 6-minute walking test (6MWT) has good universality and accessibility, and can be used as the basis for formulating exercise prescriptions. According to the consensus of Chinese experts on the application of clinical norms of the six-minute walking test, it is recommended to formulate individualized exercise prescriptions based on the average walking speed of 6MWT calculated from the six-minute walking distance (6MWD), but there is no relevant content about hypertension.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Enrollment
126
Exercise mode: walk Frequency: 5 times/week
Exercise mode: walk Frequency: 5 times/week
Regular exercise
Systolic blood pressure, SBP
systolic blood pressure (mmHg)
Time frame: through study completion, an average of 1 year
Diastolic blood pressure, DBP
diastolic blood pressure (mmHg)
Time frame: through study completion, an average of 1 year
Heart rate, HR
Heart rate (beats/min)
Time frame: through study completion, an average of 1 year
Pulse wave velocity, PWV
pulse wave velocity
Time frame: through study completion, an average of 1 year
PWV
pulse wave velocity
Time frame: through study completion, an average of 1 year
weight
weight (kg)
Time frame: through study completion, an average of 1 year
Body mass index, BMI
body mass index （kg/m\^2）
Time frame: through study completion, an average of 1 year
Blood lipids
Triglyceride, total cholesterol, low-density lipoprotein cholesterol
Time frame: through study completion, an average of 1 year
exercise hypertension
yes/no
Time frame: through study completion, an average of 1 year
circadian rhythm of blood pressure
Ambulatory blood pressure monitoring
Time frame: through study completion, an average of 1 year
anxiety
Anxiety score using Generalized Anxiety Disorder (GAD-7). High GAD-7 scores significantly predicted worse state of anxiety: no anxiety,0-4 scores; mild anxiety,5-9 scores; moderate anxiety,10-14 scores; severe anxiety,15-21 scores.
Time frame: through study completion, an average of 1 year
depression
Depression score using Patient Health Questionnaire-9 (PHQ-9). High PHQ-9 scores significantly predicted worse state of depression: no depression,0-4 scores; mild depression,5-9 scores; moderate depression,10-14 scores; severe depression,15-27 scores.
Time frame: through study completion, an average of 1 year
use of antihypertensive drugs
Record dosage and numbers of antihypertensive drugs using questionnaires.
Time frame: through study completion, an average of 1 year
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