The proposed research is a randomized crossover trial designed to assess changes in postprandial cognitive function and the gut-brain axis in adults with subjective cognitive complaints who consume 1 study snack per day for 1 week.
Study objective including 1. To measure the impact of dietary fats on postprandial cognitive function in adults who report subjective cognitive complaints. 2. To assess the effect of dietary fat consumption on the gut-brain axis in relationship to cognitive function.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Enrollment
88
56g of walnuts consumed each day for 7 days
68g of the white chocolate style-bar each day for 7 days
The Ohio State University
Columbus, Ohio, United States
RECRUITINGCognitive function measured using the National Institutes of Health Toolbox for the Assessment of Neurological and Behavioral Function Cognitive Battery (NIHTB-CB)
To determine the impact of consuming the study dietary fats as part of a high fat meal on postprandial cognitive function
Time frame: Week 0 and Week 5
Change in Cognitive function measured using the National Institutes of Health Toolbox for the Assessment of Neurological and Behavioral Function Cognitive Battery (NIHTB-CB)
To assess changes in cognitive function after consuming 1 serving of the dietary fats every day for 1 week
Time frame: Week 0, Week 1, Week 5 and Week 6
Changes in fecal Microbiota diversity
To assess changes in microbiota diversity of fecal samples after consuming 1 serving of the dietary fats every day for 1 week
Time frame: Week 0, Week 1, Week 5 and Week 6
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