A Registry Study of Biomarkers in Heart Valve Disease

Beijing Institute of Heart, Lung and Blood Vessel Diseases200,000 enrolled

Overview

Valvular Heart Disease, impacting 2.5% of the population, is predominantly observed in the elderly and is on the rise. The primary conditions within this category are Aortic Stenosis and Mitral Regurgitation. These conditions are linked to considerable morbidity and mortality, presenting a formidable challenge in optimizing treatment strategies. Pathophysiology of Valvular Heart Disease remains poorly known. The aim of the present study is to identify biomarkers involved in this disease using multi-omics approaches

Study Type

OBSERVATIONAL

Enrollment

200,000

Conditions

Cardiovascular Diseases

Eligibility

Sex: ALLMin age: 18 YearsMax age: 100 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * Patients clinically diagnosed with heart valve disease in Beijing Anzhen Hospital Exclusion Criteria: * Age \< 18 years * Failure to obtain medical records and ultrasound data * Refuse follow-up

Locations (1)

Beijing Anzhen Hospital

Beijing, Beijing Municipality, China

Outcomes

Primary Outcomes

All-cause death

whether recidivation happened,whether other related disease happened

Time frame: These data is collected during follow-up visit at 12 months after discharge

Secondary Outcomes

HF rehospitalization

heart failure related hospitalization within 1 years of discharge