This is a multicenter, single-arm, long-term safety and tolerability trial. A total of 300 subjects with chronic kidney disease on hemodialysis are planned to be enrolled.
Study Type
INTERVENTIONAL
Allocation
NA
Purpose
TREATMENT
Masking
NONE
Enrollment
303
SHR6508 will be administered to all the eligible subjects
Peking University People's Hospital
Beijing, Beijing Municipality, China
Incidence and severity of any adverse events that occurred during the clinical study
Time frame: through study completion, an average of 1 year
Percent change from baseline in predialysis iPTH during the EAP
Time frame: through study completion, an average of 1 year
Percent change from baseline in predialysis serum cCa during the EAP
Time frame: through study completion, an average of 1 year
Percent change from baseline in predialysis serum phosphorus during the EAP
Time frame: through study completion, an average of 1 year
Percent change from baseline in predialysis calcium-phosphorus product during the EAP
Time frame: through study completion, an average of 1 year
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