TheraPAP Equivalence Crossover Study

Inclusion Criteria: 1. AHI \> 10 on a previous PSG. 2. CPAP adherence for an average of 5 h/night in the 2 months before the study 3. BMI above 18 kg/m2, inclusive. Exclusion Criteria: 1. Current clinically significant sleep disorder other than OSA of a severity that would interfere with study participation or interpretability of data (including central sleep apnea, per central AHI \> 5 events/h). 2. Current clinically unstable cardiac disease (e.g., rhythm disturbances, coronary artery disease or cardiac failure) or poorly controlled hypertension (\>140/90mmHg). 3. Current clinically significant neurological disorder, including epilepsy/convulsions. 4. Other serious major organ system disease including renal failure, lung disease, neuromuscular disease, or liver disease. 5. Schizophrenia, schizoaffective disorder or bipolar disorder according to Diagnostic and Statistical Manual of Mental Disorders-5 (DSM 5) or International Classification of Disease tenth edition criteria. 6. Attempted suicide within 1 year prior to screening, or current suicidal ideation. 7. History of substance use disorder as defined in DSM-V within 24 months prior to Screening Visit. 8. A serious illness or infection in the past 30 days as determined by investigator. 9. Clinically significant cognitive dysfunction as determined by investigator. 10. Chronic oxygen therapy. 11. Patients with hypoglossal nerve stimulation implant. 12. Any non-previously mentioned vulnerable population. 13. Any condition that in the investigator's opinion would present an unreasonable risk to the participant, or which would interfere with their participation in the study or confound study interpretation.