The current project is dedicated to creating a comprehensive cognitive and neural assessment platform and corresponding norms tailored specifically to the older adults in Macau.
The investigators will establish this assessment platform using a combination of methods, including interviews, surveys, and expert reviews. Steps include adapting existing assessment methods to the Macau context, developing new cognitive and neural tasks, defining standardized procedures, seeking external expert input, conducting pilot tests, and validation processes, and refining both the platform and its accompanying manual.
Study Type
OBSERVATIONAL
Enrollment
300
Centre for Cognitive and Brain Sciences of the University of Macau
Macao, Macao SAR, Macau
Normative Data for the Montreal Cognitive Assessment - Chinese (Hong Kong) version
The MoCA will be administered to derive a normative data set representative of the older adult population in Macau.
Time frame: From February 2024 to January 2026
Normative Data for the Mini-Mental State Examination (MMSE)
The MMSE will be administered to derive a normative data set representative of the older adult population in Macau.
Time frame: From February 2024 to January 2026
Normative Scores for Computerized Neuropsychological Tasks
Neuropsychological tasks will be employed to measure selective attention capacity and processing speed in the study cohort. These tasks will provide quantifiable data on the efficiency and accuracy of cognitive processing. The collective performance on these tasks will be used to establish benchmark values - including means, medians, and ranges - that define the normative standards for these cognitive abilities in the population.
Time frame: From February 2024 to January 2026
Neural Activation Patterns During Cognitive Tasks as Revealed by Functional Magnetic Resonance Imaging (fMRI)
fMRI data will be collected to identify patterns of neural activation associated with cognitive task performance.
Time frame: From February 2024 to January 2026
Cerebral Hemodynamics Assessed Through Functional Near-Infrared Spectroscopy (fNIRS)
fNIRS will be employed to measure cerebral blood flow and oxygenation during cognitive tasks.
Time frame: From February 2024 to January 2026
Electrophysiological Correlates of Cognitive Activity as Measured by Electroencephalography (EEG)
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.
EEG will be utilized to record the electrical activity of the brain during cognitive tasks. Key outcome metrics will include event-related potentials (ERPs) amplitudes and latencies, with mean values and variability measures reported for the cohort.
Time frame: From February 2024 to January 2026