Virtual Reality Based Vision Test in Patients With AMD

Augenklinik Zurich West50 enrolled

Overview

To assess the usability, tolerability, and repeatability of the set of VR headset-based tasks.

In order to bridge the gap between the existing functional measures and AMD lesions, researchers are considering the use of VR tools. This study is designed to assess the contrast sensitivity function mapping test (CSF radial sweep) in an elderly population with AMD. The primary objective of this study is to assess the usability, tolerability, and repeatability of the set of VR headset-based tasks. The secondary objective of this study is to assess the relationship between the metrics generated by VR-based functional tasks and the metrics derived from conventional clinical measurements of retinal anatomy and visual function. The primary efficacy endpoint is the Contrast sensitivity function (CSF) area under curve (AUC) correlation to Snellen BCVA.

Study Type

INTERVENTIONAL

Allocation

Purpose

DIAGNOSTIC

Masking

NONE

Enrollment

Conditions

Age-Related Macular Degeneration

Interventions

Virtual Reality (VR) Contrast Function TestDIAGNOSTIC_TEST

Patients perform a new Virtual Reality (VR) Contrast Function Test

Eligibility

Sex: ALLMin age: 50 YearsMax age: 105 Years

Medical Language ↔ Plain English

Inclusion Criteria: 1. Subjects ≥18 years of age diagnosed with AMD 2. Subject Snellen BCVA score is 20/100 or better 3. Ability to undergo quality optical coherence tomography (OCT) imaging 4. Willing and able to give written informed consent Exclusion Criteria: 1. Unwilling to use headset 2. Previous negative experience with a VR headset (eg, motion sickness, discomfort) 3. Any known oculomotor impairment that would impact the ability of the subject to perform the tasks (eg, nystagmus, proptosis, apraxia of eyelid opening) 4. Any manifest neurological or cognitive condition that would impair the subject's understanding or performance on the test (eg, Alzheimer's disease, Parkinson's disease) 5. Any physical limitations that would prohibit the use of the VR headset (eg, neck problems)

Locations (1)

Augenklinik Zurich West

Zurich, Canton of Zurich, Switzerland

RECRUITING

Outcomes

Primary Outcomes

Usability, tolerability and repeatability

The primary objective of this study is to assess the usability, tolerability, and repeatability of the set of VR headset-based tasks. To assess the usability and tolerability a patient survey is performed.

Time frame: 20 minutes

Secondary Outcomes

Contrast sensitivity function (CSF)

Contrast sensitivity function (CSF) in decibel as area under curve (AUC). The CSF is also correlated to Snellen best corrected visual acuity (BCVA)

Time frame: 10 minutes

Central Contacts

Stephan Michels, MD

CONTACT

+414454517 info@augenklinik-zh.ch

Data from ClinicalTrials.gov

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