Identification of Prognostic Factors and Role of Radiotherapy in Patients With Ewing Sarcoma

Istituto Ortopedico Rizzoli400 enrolled

Overview

assess whether there is a correlation between some factors (age, sex, tumor volume, tumor site, chemotherapy-induced necrosis, radiation and biomarkers) and overall survival (OS) and relapse-free survival (RFS) in patients with Ewing sarcoma. Identification of reliable prognostic factors could help to identify high-risk patients, which may require a different treatment and follow up.

Study Type

OBSERVATIONAL

Enrollment

400

Conditions

Ewing Sarcoma

Interventions

clinical records reviewOTHER

review the medical records, radiological imaging, and histological data of these patients

Eligibility

Sex: ALLMin age: 2 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Male and female patients treated at Rizzoli Orthopaedic Institute between 01/01/1991 and 31/12/2021 * Age ≥ 2 years * Diagnosis of Ewing Sarcoma * Patients with available clinical and imaging data Exclusion Criteria: * At least one inclusion criterion not met

Locations (1)

IRCCS Itituto Ortopedico Rizzoli

Bologna, BO, Italy

RECRUITING

Outcomes

Primary Outcomes

Correlation

Correlation between some factors (age, sex, tumor volume, tumor site, chemotherapy-induced necrosis, radiation and biomarkers) and overall survival (OS) and relapse-free survival (RFS) in patients with Ewing sarcoma.

Time frame: At baseline (Day 0)

Central Contacts

Costantino Errani

CONTACT

0516366 costantino.errani@ior.it

Data from ClinicalTrials.gov

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