Ultrasound Guided Autologous Blood Injection in Temporomandibular Joint Dislocation

Cairo University24 enrolled

Overview

The aim of this study is To compare the accuracy and effectiveness of ultrasound (US) guided autologous blood injection (ABI) versus non- guided technique for the treatment of chronic recurrent temporomandibular joint dislocation

All patients involved in this study will be divided randomly to two different groups and injected with autologous blood into joint space and pericapsular tissue. Study group (group A) will be injected with autologous blood with ultrasound guidance. control group (group B) will be injected with autologous blood without US guidance. Anatomical landmarks and tactical sense will be followed only. The operation will be done under local anesthesia ( Auriculotemporal nerve block ) the skin overlying the temporomandibular joint will be scrubbed by an antiseptic solution and the area will be isolated with sterile towels. External auditory canal will be blocked with cotton. About 3 ml of blood will be withdrawn from patient's antecubital fossa, of which 2 ml injected intra-articular and 1 ml in the pericapsular tissue (PT) The procedure should be repeated on the opposite side in case of bilateral involvement.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

DOUBLE

Enrollment

Conditions

Temporomandibular Joint Dislocation

Interventions

ultrasound guided autologous blood injectionPROCEDURE

guided

non guided autologous blood injectionPROCEDURE

non guided

Eligibility

Sex: ALLMin age: 18 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * Patient with at least 3 episodes of temporomandibular joint dislocation in the past 6 months. * Necessitating a visit to the emergency room or trained professional to reduce the dislocation. * Radiological evidence of displacement of condylar head beyond the articular eminence on wide mouth opening. * Maximum mouth opening (MMO) more than 40 mm. * Unilateral or bilateral. * Over 18 years of age. * Both gender Males or females. Exclusion Criteria: * Patient having inflammatory temporomandibular joint disease like tuberculous arthritis, rheumatoid arthritis. * Patients with bleeding disorders, pregnancy or bony pathology of temporomandibular joint . * Allergy to local anesthetic. * Severe epilepsy or Parkinson's disease. * Patient on anti-depressants or anti-psychotics. * Inability to follow-up the patient during the entire follow-up period. * Patients who had recent fracture at temporomandibular joint level or who had previous surgical interference to temporomandibular joint . * Refused to sign the written informed consent were also excluded. * Dystonia

Locations (1)

faculty of dentistry, Cairo university

Cairo, Egypt

RECRUITING

Outcomes

Primary Outcomes

maximum mouth opening

change in Maximum mouth opening (MMO): It's measured (in millimeter) from incisal edge of 11 to 41, in maximum mouth open position using caliper

Time frame: at 2weeks, 3months and 6 months post-operative

Secondary Outcomes

Frequency of temporomandibular joint dislocation:

number of dislocation per week

Time frame: 2weeks, 3 months and 6 months post-operatively

change of pain

measuring pain using visual analogue scale(0-10),higher scores mean worse outcome.

Time frame: 2weeks, 3 months and 6 months post-operatively

Central Contacts

Mohamed Abbas, bachelor

CONTACT

01157370918 mohamed.abbas@dentistry.cu.edu.eg

Data from ClinicalTrials.gov

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