This observational research study is designed to assess the feasibility of developing a new software application that can be used in the home using a commercially available camera to measure abnormal body movements associated with Parkinson's disease (PD). The goal of this study is to validate the motor outcomes derived from a consumer camera observing a sub-set of standardized assessment tasks with respect to the reference motion capture system.
The long-term goal of this project is to develop a new software application (NeuroVision App) for a smartphone or tablet that can be used in the home to measure abnormal body movements associated with Parkinson's disease (PD). The outcomes are intended to enhance PD symptom monitoring in the context of telehealth videoconferences with a clinician. Typical abnormal body movements that can be assessed with the proposed solution include uncontrolled shaking of hands and limbs (tremor) or spastic movements (dyskinesia) while at rest; abnormally slow movements when reaching or walking (bradykinesia); or inability to initiate a movement (akinesia) using 5 standardized motor assessment tasks (sitting at rest, walking, finger tapping, foot tapping, and foot stomping) derived from the Unified Parkinsons Disease Rating Scale (UPDRS). The proposed solution will make it easier for the doctor to periodically assess the motor signs of PD during remote telehealth appointments which may be more convenient and safer for the patient. Current reliance on videoconferencing apps make it difficult to record and measure such symptoms accurately in a telehealth setting.
Study Type
OBSERVATIONAL
Enrollment
20
Altec Inc.
Natick, Massachusetts, United States
RECRUITINGTremor Duration
Duration in seconds of resting tremor in the hands obtained using the NeuroVision prototype while the subject is sitting at rest.
Time frame: 2 minute
Tremor Amplitude
Amplitude in centimeters of resting tremor in the hands obtained using the NeuroVision prototype while the subject is sitting at rest.
Time frame: 2 minute
Parkinsonian Gait - Step Length
Step length in centimeters obtained using the NeuroVision prototype while the subject is walking.
Time frame: 5 minute
Parkinsonian Gait - Step Time
Step time in seconds obtained using the NeuroVision prototype while the subject is walking.
Time frame: 5 minute
Parkinsonian Gait - Step Variability
Step variability in centimeters obtained using the NeuroVision prototype while the subject is walking.
Time frame: 5 minute
Bradykinesia Finger Tap Duration
Duration in seconds of a finger tapping task obtained using the NeuroVision prototype while the subject opens and closes their hand as rapidly as possible.
Time frame: 2 minute
Bradykinesia Finger Tap Amplitude
Amplitude in centimeters of a finger tapping task obtained using the NeuroVision prototype while the subject opens and closes their hand as rapidly as possible.
Time frame: 2 minute
Bradykinesia Foot Tap Duration
Duration in seconds of a foot tapping task obtained using the NeuroVision prototype while the subject taps their toes on the floor as rapidly as possible.
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Time frame: 2 minute
Bradykinesia Foot Tap Amplitude
Amplitude in centimeters of a foot tapping task obtained using the NeuroVision prototype while the subject taps their toes on the floor as rapidly as possible.
Time frame: 2 minute
Bradykinesia Foot Stomping Duration
Duration in seconds of a foot stomping task obtained using the NeuroVision prototype while the subject lifts and lowers their foot on the floor as rapidly as possible.
Time frame: 2 minute
Bradykinesia Foot Stomping Amplitude
Amplitude in centimeters of a foot stomping task obtained using the NeuroVision prototype while the subject lifts and lowers their foot on the floor as rapidly as possible.
Time frame: 2 minute