Serum and Urine Metabolome Studies in Patients With Acute Kidney Injury After Cardiac Surgery

Nanjing First Hospital, Nanjing Medical University200 enrolled

Overview

The goal of this observational study is to learn about serum and urine metabolome in patients after cardiac surgery.

The main objective of this study is to collect blood and urine samples from patients after cardiac surgery, and to perform metabolomic analysis to find the differential metabolites and their enrichment pathways in AKI patients and non-AKI patients.The secondary objective is to intervene in its enrichment pathway to find ways to improve CSA-AKI.

Study Type

OBSERVATIONAL

Enrollment

200

Conditions

Cardiac Surgery Associated Acute Kidney Injury

Interventions

OTHER

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: 1. Age\> 18 years old; 2. after cardiopulmonary bypass; Exclusion Criteria: 1. Under the age of 18; 2. Previous chronic kidney disease or receiving renal replacement therapy; 3. Have a history of kidney transplantation or nephrectomy.

Locations (1)

Nanjing First Hospital

Nanjing, China

Outcomes

Primary Outcomes

serum and urine metabolome studies

The preoperative and postoperative metabolomic differences in blood and urine between AKI group and non-AKI group were compared.

Time frame: January 2025 - December 2025

Data from ClinicalTrials.gov

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