Severe Head Trauma: Coagulation and CT-Scan Aggravation.

Centre Hospitalier Annecy Genevois23 enrolled

Overview

Retrospective, multicenter cohort study describing the biological, radiological and clinical criteria of patients managed for isolated severe head trauma between January 2016 and December 2018.

The objective of the study is to describe the evolution of CTscan lesions in patients with isolated Head Trauma between admission and re-evaluation after 24 hours.

Study Type

OBSERVATIONAL

Enrollment

Conditions

Head Trauma

Interventions

No interventionOTHER

No intervention

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Adults * Patients informed and did not object to the collection of their medical data for the study * Patient admitted in Trauma center between January 2016 and December 2018 severe head injury defined by a Glasgow Coma Scale (GCS) \< 9 AND/OR Abnormalities on the first brain CT-scan with pathological transcranial Doppler (Vd \< 25 cm/s and IP \> 1.25) Exclusion Criteria: * Abbreviated Injury Score (AIS) head and neck ≤ 3 AND/OR AIS out of head and neck \> 3 * Taking drugs that interfere with hemostasis, such as anticoagulant or antiplatelet antiaggregants in preventive or curative doses; * Patients under guardianship * Patients still alive at the time of data collection AND opposed to the collection of their data

Locations (1)

Centre Hospitalier Annecy Genevois

Pringy, France

Outcomes

Primary Outcomes

Describe the evolution of CT scan lesions between admission and reassessment CT scan

Number of patient with an aggravation of lesions on CT scan

Time frame: 24 hours

Secondary Outcomes

Mortality

Mortality rate

Time frame: Day 28

Causes of death

Time frame: Day 28

Describe the coagulation status on admission with severe head trauma trauma

Fibrinogen level values

Time frame: 24 hours

Describe the coagulation status on admission with severe head trauma trauma

Platelet count values

Time frame: 24 hours

Describe the coagulation status on admission with severe head trauma trauma

INR values

Time frame: 24 hours

Describe the coagulation status on admission with severe head trauma trauma

ROTEM values

Time frame: 24 hours

Data from ClinicalTrials.gov

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