The aim of this randomized, single-masked, controlled clinical trial study was to determine if the administration of electro acupuncture improves the outcomes obtained in combination with non-surgical periodontal therapy. Participants will get non-surgical periodontal therap with/without electro acupuncture. Researchers will compare EA and control groups to see if there is any relationship between acupuncture application clinical periodontal parameters,serum and saliva cytokine levels.
Periodontitis is a prevalent complex chronic inflammatory oral disease that can result in the progressive destruction of tooth supporting tissues and eventual loss of teeth. Although pathogenic bacteria are the triggers and provokers of periodontal inflammation, the main determinant of the destruction is the host immunoinflammatory response. The host response is modified by many genetic and environmental factors as well as various systemic diseases. Electroacupuncture (EA) has effects on both the immune system and inflammatory processes. The effect of acupuncture on the regulation of cytokine production has been mentioned in the literature. . No study has been found in the literature about the effects of EA on the host modulation in periodontitis patients. In this study, the investigators aimed to examine the effect of electroacupuncture application on the host modulation at periodontitis.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
TRIPLE
Enrollment
52
LI-4, LI-11, GV-14, GV-20 acupuncture points were needled bilaterally.
Atatürk University
Erzurum, Turkey (Türkiye)
Clinical periodontal parameters / clinical attachment level (CAL)
CAL was measured as the distance between the deepest point of the sulcus and the cemento-enamel junction
Time frame: Baseline-week 3
Clinical periodontal parameters / probing pocket depth (PPD)
PPD was measured as the distance between the deepest point of the sulcus and the gingival margin
Time frame: Baseline-week 3
Clinical periodontal parameters / bleeding on probing (BOP)
The presence of bleeding on probing is considered an objective sign of periodontal inflammation
Time frame: Baseline-week 3
Clinical periodontal parameters / plaque index (PI)
The amount of plaque present on the teeth was assessed using a plaque staining agent and graded according to the plaque index system
Time frame: Baseline-week 3
Clinical periodontal parameters / gingival index (GI)
The presence and extent of gingival inflammation and bleeding were graded according to the gingival index system
Time frame: Baseline-week 3
Biochemical findings
IL-6, IL-10, TNF-α
Time frame: Baseline-day 7-week 3
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