Lymphatic System Reflux After Lymphatic Operation

Chang Gung Memorial Hospital79 enrolled

Overview

This study aimed to determine the impact on outcomes when recipient veins with reflux were used for LVA for the treatment of unilateral lower limb lymphedema.

The use of recipient veins with reflux for lymphaticovenous anastomosis (LVA) is discouraged because of the common belief that it may lead to venous-lymphatic reflux (VLR), a phenomenon in which venous blood is refluxed into the lymphatic lumen after anastomosis, which can lower the long-term patency rate. However, this concept has yet to be validated.

Study Type

OBSERVATIONAL

Enrollment

Conditions

Lymphedema

Interventions

Veins with refluxOTHER

This group included patients who used only recipient veins with reflux

Reflux-free recipient veinsOTHER

This group included patients who utilized only reflux-free recipient veins

Eligibility

Sex: ALLMin age: 20 YearsMax age: 100 Years

Medical Language ↔ Plain English

Inclusion Criteria: * This study including patients diagnosed with lymphatic-related diseases at Kaohsiung Chang Gung Memorial Hospital from October 1, 2015, to December 31, 2022. * Patients who underwent LVA for unilateral lower-limb lymphedema. Exclusion Criteria: * Patients under the age of 20. * Patients lost to follow-up or with incomplete data.

Locations (1)

Kaohsiung Chang Gung Memorial Hospital

Kaohsiung City, Taiwan

Outcomes

Primary Outcomes

Volume change after LVA.

The primary endpoint was the volume change at 6/12 months after LVA.

Time frame: 6/12 months

Data from ClinicalTrials.gov

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