Comparative Analysis of Radiotherapeutic and Medical Procedures for the Prophylaxis of Heterotopic Ossifications

University of Jena512 enrolled

Overview

Aim of this study is to proof the efficacy of in Jena established prophylaxis of new bone formation aside the skeleton with irradiation and compare it with the common literature. Furthermore we want to compare irradiation treatment with the alternative prophylaxis with analgetics from the NSAID type.

Aim of this retrospective analysis is to compare the incidence of heterotopic ossification one year after total hip arthroplasty with the at our location established concept of irradiation 24h preoperative and incidence in common literature. Furthermore the comparison between irradiated patients and patients treated with NSAIDs.

Study Type

OBSERVATIONAL

Enrollment

512

Conditions

Heterotopic Ossification Hip Arthropathy Myositis Ossificans Traumatica, Thigh

Interventions

RadiationRADIATION

Single dose radiation with 7-8 Gy

DiclofenacDRUG

postoperative treatment with diclofenac to prevent HO

Eligibility

Sex: ALL

Medical Language ↔ Plain English

Inclusion Criteria: Patients with total hip arthroplasty performed at Eisenberg Patients with preoperative irradiation (24h pre-op) or postoperative diclofenac treatment Patients with x-ray images immediately (3-5 days postoperative) postoperative and at least 365 days postoperative Exclusion Criteria: Patients with missing follow up image

Locations (1)

Department of Radiooncology, Jena

Jena, Germany

Outcomes

Primary Outcomes

Presence of heterotopic ossification (HO)

X-ray controlled HO diagnostics with the Brooker classification

Time frame: at least 365 days postoperative

Data from ClinicalTrials.gov

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