Collection of Ocular Surface Impressions Cytology of the Living Eye From Patients With Dry Eyes or Limbal Stem Cell Deficiency.

Centre Hospitalier Universitaire de Saint Etienne300 enrolled

Overview

In order to develop innovative biomarkers for the diagnosis of two ocular surface pathologies, Dry Syndrome (DS) and Limbic Stem Cell Deficiency (LSCD), human cells from the ocular surface will be collected in order to test these biomarkers ex vivo.

To collect them, cytological fingerprints of the ocular surface are made using filter paper applied to the surface using a commercially available EC (European Conformity)-marked medical device, called EYEPRIM.

Study Type

OBSERVATIONAL

Enrollment

300

Conditions

Eye Diseases

Interventions

EYEPRIMDIAGNOSTIC_TEST

Collection of conjunctival impressions using the EC(European Conformity )-marked EYEPRIM device . This device enables cells to be collected the superficial ocular surface cells by applying a membrane for few seconds to the ocular surface.

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Patient affiliated or entitled to a social security scheme * Age 18 years or older * Presenting a Dry Syndrome, a limbic stem cell deficiency (clinical diagnosis) or another pathology (control). * Signature of Consent Exclusion Criteria: * Major blepharospasm making examination impossible * Pregnant women * Breastfeeding women * Protected Persons

Locations (1)

CHU Saint-Etienne

Saint-Etienne, France

Outcomes

Primary Outcomes

Ocular surface impression cytology collected from patients suffering from dry eye syndrome, limbal stem cell deficiency or other pathologies (control).

Collection of cells from the ocular surface by performing a cytological imprint of the ocular surface

Time frame: day one

Data from ClinicalTrials.gov

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