In patients with Multiple Myeloma (MM), bone lesions can lead to multiple vertebral lesions, with vertebral collapses. The introduction of minimally invasive procedures such as percutaneous vertebroplasty allow patients to return to a fair level of function and a significant reduction in pain. Despite medical therapies, radiotherapy, analgesics and vertebroplasty procedures, patients with multiple spinal injuries often complain of pain and stiffness that limit their mobility, daily activities and work. The aim of this study is to measure how the biomechanical, thermo-metabolic and algic parameters change after vertebroplasty in patients with MM
In patients with Multiple Myeloma (MM), bone lesions can lead to multiple vertebral lesions, with vertebral collapses. The introduction of minimally invasive procedures such as percutaneous vertebroplasty allow patients to return to a fair level of function and a significant reduction in pain. Despite medical therapies, radiotherapy, analgesics and vertebroplasty procedures, patients with multiple spinal injuries often complain of pain and stiffness that limit their mobility, daily activities and work. The aim of this study is to measure how the biomechanical, thermo-metabolic and algic parameters change after vertebroplasty in patients with MM
Study Type
OBSERVATIONAL
Enrollment
20
Centro di Riferimento Oncologico (CRO) di Aviano - IRCCS
Aviano, Pordenone, Italy
RECRUITINGDifference in mean of kinematic data for walking before and after vertebroplasty
Difference in mean of kinematic data for walking before and after vertebroplasty
Time frame: 2 months
difference in mean of movement range for affected joints before and after vertebroplasty
difference in mean of movement range for affected joints before and after vertebroplasty
Time frame: 2 months
Difference in mean of energy expenditure before and after vertebroplasty
Difference in mean of energy expenditure before and after vertebroplasty
Time frame: 2 months
To explore the impact of vertebroplasty on thermal parameters
Central and superficial temperature will be measured before and after vertebroplasty. Difference will be reported as intrapatient mean difference
Time frame: 2 months
To explore the impact of vertebroplasty on metabolic parameters
Carbon dioxide production after 30 minutes of walking will be measured before and after vertebroplasty and intrapatient mean difference will be reported.
Time frame: 2 months
To explore the impact of vertebroplasty on metabolic parameters
Cardiac frequency after 30 minutes of walking will be measured before and after vertebroplasty and intrapatient mean difference will be reported.
Time frame: 2 months
To explore the impact of vertebroplasty on metabolic parameters
Oxygen consumption after 30 minutes of walking will be measured before and after vertebroplasty and intrapatient mean difference will be reported.
Time frame: 2 months
To explore the impact of vertebroplasty on pain
Perceived pain will be measured using the Brief Pain Inventory scale (BPI) before and after vertebroplasty. Difference will be reported as intrapatient mean difference. BPI values range between 0 and 10, with higher scores meaning worst pain
Time frame: 2 months
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