Correlation of Antibody Response to COVID-19 Vaccination in Pregnant Woman and Transplacental Passage Into Cord Blood.

Vachira Phuket Hospital40 enrolled

Overview

The goal of this study is to study the correlation of maternal and cord blood level of Anti SAR-CoV.

The goal of this study is to study the correlation of maternal and cord blood level of Anti SAR-CoV. Sample size is 40 Thai patients at labor room Vachira Phuket Hospital in October - November 2023, who have at least one COVID-19 vaccination before or when pregnant. The Secondary outcome is to study time effect after COVID-19 vaccination and effect of vaccine type on Antibody level.

Study Type

INTERVENTIONAL

Allocation

Purpose

HEALTH_SERVICES_RESEARCH

Masking

NONE

Enrollment

Conditions

Covid-19

Interventions

COVID-19 Spike Protein IgG Quantitative Antibody (CMIA)DIAGNOSTIC_TEST

Maternal blood and cord blood were collected to test for COVID-19 Spike Protein IgG Quantitative Antibody (CMIA)

Eligibility

Sex: FEMALEMin age: 18 YearsMax age: 45 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * Thai term pregnant women * 18-45 year old * At least 1 covid vaccination received * admission at Vachira Phuket Hospital Labor Room Exclusion Criteria: * Do not want to participate * Unstable or Emergency condition

Locations (1)

Vachira Phuket Hospital

Phuket, Thailand

Outcomes

Primary Outcomes

COVID-19 Spike Protein IgG Quantitative Antibody (CMIA) Level

Test for correlation of level in maternal and cord blood

Time frame: 1 month

Secondary Outcomes

Analysed time effect from last vaccination and type.

Test for time effect after last dose of vaccination

Time frame: 1 month

Data from ClinicalTrials.gov

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