Mindfulness Meditation Combined With Progressive Muscle Relaxation Training for Uremic Sarcopenia

Ningbo Medical Center Lihuili Hospital49 enrolled

Overview

To study the effect of mindfulness meditation combined with progressive muscle relaxation training on clinical efficacy and quality of life in maintenance hemodialysis (MHD) patients with sarcopenia. Eligible sarcopenic patients in our hospital were randomly assigned to a control group (n = 24) and an intervention group (n = 25). The control group received conventional dialysis treatment, while the intervention group received mindfulness meditation combined with progressive muscle relaxation training during the interdialysis period in addition to conventional dialysis treatment. The effect of the intervention was evaluated after 12 weeks.To observe whether the combined intervention training can improve the motor ability and quality of life of patients with sarcopenia in a short period of time.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

NONE

Enrollment

Conditions

Hemodialysis Patients With Sarcopenia

Interventions

Eligibility

Sex: ALLMin age: 18 YearsMax age: 80 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Patients who met the sarcopenia criteria established by the Asian Working Group for Sarcopenia (AWGS) in 2014 * Stable condition and generally good health status * Good compliance and ability to collaborate well with the physician * Undergoing hemodialysis three times per week for at least three months, with a KT/V ≥ 1.2 * No significant cardiovascular or cerebrovascular complications (such as severe heart failure, severe arrhythmias, angina, and cerebrovascular diseases) * Patients with sarcopenia who met the clinical diagnostic criteria were selected to ensure the quality of the included patients Exclusion Criteria: * Inability to complete handgrip strength, 6-meter walk test, 10 sit-to-stand tests, and the use of bioelectrical impedance analysis (BIA) due to contraindications * Coexistence of mental illness or severe cognitive or communication disorders

Outcomes

Primary Outcomes

10 sit-to-stand test in seconds

The 10 sit-stand test represents exercise ability, and the shorter the time, the greater the exercise ability.

Time frame: 3 months

Grip strength in kilograms

Grip strength represents exercise ability, and the larger it is, the more exercise ability it is.Its minimum value is zero, and its maximum value is unlimited.

Time frame: 3 months

6-meter walk test in metre per second

6-meter walk test represents exercise ability, and the larger it is, the more exercise ability it is.Its minimum value is zero metre per second, and its maximum value is unlimited.

Time frame: 3 months

KDQOLTM(Kidney Disease Quality of Life short Form) score

The KDQOLTM score is between 0 and 100, and the higher the score, the better the health

Time frame: 3 months

interleukin-6 (IL-6)

Interleukin 6 represents an inflammatory marker, and its concentration is 20pg/ml or less.

Time frame: 3 months

high-sensitivity C-reactive protein (hsCRP)

hsCRP represents an inflammatory marker, and its concentration ranges from 0.0 to 10mg/L.

Time frame: 3 months

albumin(ALB)

Albumin represents a nutritional indicator, and its concentration ranges from 40 to 55g/L.

Time frame: 3 months

prealbumin (PA）

Prealbumin represents a nutritional indicator, and its concentration ranges from 0.20 to 0.43g/l.

Time frame: 3 months

Mindfulness Meditation Combined With Progressive Muscle Relaxation Training for Uremic Sarcopenia

Overview

Conditions

Interventions

Eligibility

Locations (1)

Outcomes

Primary Outcomes