The goal of this clinical trial is to evaluate if prophylactic antibiotics in urethral bulking are effective in reducing postprocedural urinary tract infections.
Urethral bulking is a minimally invasive surgical treatment option for stress urinary incontinence (SUI). One commonly reported post-procedural complication is urinary tract infection (UTI). UTI rates are variable where studies have reported rates from as low as 0% to as high as 40%. Along with this variability, the instructional inserts for various bulking agents have inconsistent recommendations for use of prophylactic antibiotics. The American Urologic Association recommends antimicrobial prophylaxis for cystourethroscopy procedures involving minor manipulation. Currently, there are no clear guidelines regarding the utility of prophylactic antibiotics for urethral bulking. The objective of our study is to determine the effectiveness of prophylactic antibiotics in urethral bulking for reducing post procedural UTIs.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
NONE
Enrollment
70
These participants will be given a single dose of an oral antibiotic prior to the procedure.
These participants will not be given an antibiotic prior to the procedure.
Atlantic Health
Morristown, New Jersey, United States
RECRUITINGRate of urinary tract infection (UTI)
The rate of UTI based on symptoms and a positive urine culture
Time frame: Within 4 weeks after the procedure
Rate of postoperative urinary retention
The rate of postoperative urinary retention
Time frame: Within 4 weeks after the procedure
Rates of other postoperative complications
The rate of other complications (bleeding, discomfort, etc)
Time frame: Within 4 weeks after the procedure
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