Severity Over Time of Early Forms of Spondyloarthritis

N/ANot Yet RecruitingNCT06261931

Fondazione Policlinico Universitario Agostino Gemelli IRCCS387 enrolled

Overview

Spondyloarthritis (SpA) is a group of chronic inflammatory pathologies whose progression over time is poorly defined, and in particular the clinical and instrumental elements that can predispose to a condition of disease severity are not completely known. It would be important to have an idea of what the predisposing factors are, possibly already at baseline, and possibly also at follow up, of severe disease, so as to be able to act early with more aggressive and targeted therapies on these patients, so as to achieve remission.

Study Type

OBSERVATIONAL

Enrollment

387

Conditions

Spondyloarthritis Spondyloarthritis, Axial

Interventions

Diagnostic assessmentDIAGNOSTIC_TEST

patient with sponiloarthritis who comes to the clinic Hospital for clinical evaluation of disease. Assessment instrumental evaluation of the axial involvment t, with x-ray of the spine and pelvis every 5 years, and MRI of the spine and pelvis every 2 years.

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * age \>18 years; * Diagnosis of SpA confirmed by the rheumatologist with duration of symptoms \< * 2 years; * Signature of the written informed consent to the study Exclusion Criteria: * Age \< 18 years; * Patients suffering from other rheumatic pathologies (even in overlap), or genetic diseases such as Marfan syndrome, Ehlers Danlos syndrome * Any medical or psychiatric condition that in the judgment of the investigator would prevent the participant from complying with the protocol or completing the study according to the protocol. * Refusal to sign the informed consent to the study.

Outcomes

Primary Outcomes

spondyloarthritis severity

evaluation of disease severity at 10 years in the entire study population

Time frame: t0 baseline 3hours, t1 3 months 3hours,t2 6 months 3hours,t2 12months 3hours,every six months up to the tenth year