Evaluation of the Effects of Routine Intake of Fresh vs- Pasteurized Yoghurt on the Immune System in Healthy Adults

Inclusion criteria * Age between 20 and 70 years, both included. * Healthy or mildly ill subjects (without any current chronic pharmacotherapy). * Body mass index between 18.5 and 29.9 kg/m2, both included. * Subjects who usually follow a balanced diet that are not engaged in any therapeutic lifestyle change involving stringent dietary interventions such as weight-reducing diets. * Written informed consent to participate Exclusion criteria * Patients could not meet any the following criteria at the screening visit to be included in the study. * Subjects with diseases or disorders affecting the function of the immune system, such as auto-immune diseases, allergies, atopic conditions, hypersensitivity to any kind of stimulus, or immunosupression for any reason; even if they are not currently taken any pharmacotherapy. * Subjects with relevant functional or structural disorder affecting the gastrointestinal tract, such as malformations, angiodysplasias, active peptic ulcers or chronic inflammatory disease of the intestine; even if they are not in any specific pharmacotherapy at the time of recruitment; or who have underwent surgical procedures with permanent sequels (for example, gastroenterostomy). * Subjects with any infectious disease requiring antibiotherapy at the time of recruitment. * Subjects following any treatment modifying the immune response, such as immunosuppressants, corticosteroids, etc. * Subjects with celiac disease. * Subjects with chronic background weakening conditions, such as diabetes or neoplasms. * Subjects with history of renal lithiasis. * Subjects with deficient nutritional or hydrational status. * Subjects with relevant deviations in routine haematology or biochemistry parameters. * Subjects with current and documented alcohol abuse. * Subjects in whom the investigator expected insufficient collaboration or difficulties to follow the study procedures. * Subjects who regularly took any of the forbidden products specified in the appropriate section.