The objective of this retrospective, prospective, multicenter cohort study is to determine the risk factors for deterioration of CVT patients after admission and establish a scoring model for risk stratification of patients. This study included two stages, the first stage was to enroll CVT patients from a single center from 2017 to 2022 for modeling, and the second stage was to enroll CVT patients from three centers in 2023 for external validation
Study Type
OBSERVATIONAL
Enrollment
273
Capital Medical University Affiliated Beijing Tiantan Hospital
Beijing, Beijing Municipality, China
Number of Participants with CVT deteriorated on radiology
One of the following situations occurs: new or progressive bleeding or infarction, midline displacement (\>3mm), increased cerebral edema, and placeholder effect by comparing the CT before and after; mRS and/or GCS decreased due to decreased consciousness, increased focal neurological impairment, new focal neurological impairment or death.
Time frame: After admission until discharge, a maximum of 30 days
Number of Participants with altered neurological function
mRS Score decreased due to decreased consciousness, increased focal neurological impairment, new focal neurological impairment or death.
Time frame: After admission until discharge, a maximum of 30 days
Number of Participants with altered consciousness
GCS Score decreased
Time frame: After admission until discharge, a maximum of 30 days
Neurological function at 30th day after onset (mRS)
MRS was used to evaluate the neurological function of patients at 30th day after onset.
Time frame: 30th day after onset
Emergency surgery rates
Rate of patients receiving emergency surgery for severe brain edema or hernia (including endovascular treatment and bone flap decompression).
Time frame: After admission until discharge, a maximum of 30 days
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