The purpose of this study was to evaluate the efficacy and safety of tiragolumab plus atezolizumab compared with placebo plus atezolizumab administered to participants with non-small cell lung cancer (NSCLC) following resection and adjuvant chemotherapy.
With Protocol Amendment 2, enrollment will be stopped. The primary objective of the study has been changed to a safety objective and no other analysis will be conducted
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Enrollment
56
Atezolizumab will be administered IV.
Tiragolumab will be administered IV.
Placebo will be administered IV.
Number of Participants With Adverse Events (AEs)
An AE was defined as any untoward medical occurrence in a participant or clinical study participant temporally associated with the use of a study treatment, whether or not considered related to the study treatment. An AE was therefore any unfavorable and unintended sign (including an abnormal laboratory finding), symptom, or disease (new or exacerbated) temporally associated with the use of the study intervention.
Time frame: Up to 16.4 months
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Centro Oncologico Korben
Ciudad Autonoma Buenos Aires, Argentina
Sunshine Coast University Hospital
Birtinya, Queensland, Australia
Monash Health
Clayton, Victoria, Australia
Crio - Centro Regional Integrado de Oncologia
Fortaleza, Ceará, Brazil
Nucleo de Oncologia da Bahia - NOB
Salvador, Bahia, Estado de Bahia, Brazil
Hospital de Clínicas de Passo Fundo
Passo Fundo, Rio Grande do Sul, Brazil
Hospital Nossa Senhora da Conceicao
Porto Alegre, Rio Grande do Sul, Brazil
Hospital de Cancer de Barretos
Barretos, São Paulo, Brazil
Changzhou First People's Hospital
Changzhou, China
The First Affiliated Hospital of Sun Yat-sen University
Guangzhou, China
...and 27 more locations