This is a pilot research study to test the protocols needed for transcutaneous spinal electrical stimulation in persons living with spinal cord injury (SCI). Up to 24 participants will be enrolled. A variety of stimulation parameters and outcome measures will be assessed.
Purpose of this project Spinal cord stimulation has the potential to improve motor function recovery after spinal cord injury. Commonly used approaches include low-intensity, direct current (DC) stimulation applied across multiple segments, electrical transcutaneous (ETC) stimulation, and magnetic transcutaneous stimulation (MTC). Objective: to evaluate and compare the voluntary and reflexive motor performance in the same subjects, including people with and without spinal cord injury, after non-invasive spinal cord stimulation interventions. Comparing two different interventions applied in different experimental sessions and the respective sham stimulation is the goal of this study. corticospinal and spinal motor pathways in paraplegics and in non-injured humans will be tested.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
DOUBLE
Enrollment
24
transcutaneous spinal stimulation by direct current stimulation
sham transcutaneous spinal stimulation by direct current stimulation
transcutaneous spinal stimulation by electrical pulsed stimulation
University of Manitoba
Winnipeg, Manitoba, Canada
ENROLLING_BY_INVITATIONUniversity of Manitoba
Winnipeg, Manitoba, Canada
RECRUITINGMotor response
H-reflex input output curve
Time frame: Immediately after stimulation (within 1-15 min)
Motor evoked potentials
MEP input-output curve
Time frame: Immediately after stimulation (within 1-15 min)
Blood pressure
Measured (in arm) with inflatable cuff-automated, standard machine.
Time frame: During the procedure/stimulation and up to 15 min after stimulation.
Perception of discomfort due to stimulation
self-reporting on a scale ( the higher, the more discomfort)
Time frame: During and after procedure/stimulation and up to 15 min after stimulation.
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.
sham transcutaneous spinal stimulation by electrical pulsed stimulation