No studies to date to evaluate the effects of the three different liquid IV electrolyte products on the beverage hydration index (BHI). Therefore, the purpose of this study is to determine the impact of three different LIV products (Hydration multiplier, Sugar Free formulation with Amino Acids, and Sugar Free with allulose) on hydration status in young and active men and women compared to a control (water). The study will follow the same approach as used by Maughan and colleagues (2016) to measure the fluid balance (the difference between the amount of water consumed and passed as urine) and BHI (the relative amount of urine passed after consumption of a drink compared to water) including time in positive fluid balance, as well as determining electrolyte concentrations, osmolality, specific gravity, and sodium and potassium in urine.
Many attempts have been made to improve and measure the hydration status of active individuals. This typically involves the ingestion of fluids leading up to activity (typically plain water), as well as the ingestion of fluids during the activity itself (water, along with a diluted carbohydrate/electrolyte beverage). This approach seems to work well; however, some debate remains over what the best fluid is to consume, in particular related to the macronutrient type and the specific electrolyte mix. No studies to date to evaluate the effects of the three different liquid IV electrolyte products on the beverage hydration index (BHI). Therefore, the purpose of this study is to determine the impact of three different LIV products (Hydration multiplier, Sugar Free formulation with Amino Acids, and Sugar Free with allulose) on hydration status in young and active men and women compared to a control (water). The study will follow the same approach as used by Maughan and colleagues (2016) to measure the fluid balance (the difference between the amount of water consumed and passed as urine) and BHI (the relative amount of urine passed after consumption of a drink compared to water) including time in positive fluid balance, as well as determining electrolyte concentrations, osmolality, specific gravity, and sodium and potassium in urine.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
SINGLE
Enrollment
28
Subjects will consume 1 Liter (2 servings) of commercially available Hydration Multiplier product at a rate of 250 milliliters per 7.5 minutes.
Subjects will consume 1 Liter (2 servings) of experimental Sugar Free Hydration Multiplier product at a rate of 250 milliliters per 7.5 minutes.
Subjects will consume 1 Liter (2 servings) of commercially available Sugar Free Hydration Multiplier product that contains amino acids at a rate of 250 milliliters per 7.5 minutes.
Subjects will consume 1 Liter of water at a rate of 250 milliliters per 7.5 minutes.
Center for Nutraceutical and Dietary Supplement Research
Memphis, Tennessee, United States
Beverage Hydration Index
Beverage Hydration index calculated as mass of urine collected following control (water) consumption divided by the mass of urine collected following treatment.
Time frame: 0 minutes after beverage consumption
Beverage Hydration Index
Beverage Hydration index calculated as mass of urine collected following control (water) consumption divided by the mass of urine collected following treatment.
Time frame: 60 minutes after beverage consumption
Beverage Hydration Index
Beverage Hydration index calculated as mass of urine collected following control (water) consumption divided by the mass of urine collected following treatment.
Time frame: 120 minutes after beverage consumption
Beverage Hydration Index
Beverage Hydration index calculated as mass of urine collected following control (water) consumption divided by the mass of urine collected following treatment.
Time frame: 180 minutes after beverage consumption
Beverage Hydration Index
Beverage Hydration index calculated as mass of urine collected following control (water) consumption divided by the mass of urine collected following treatment.
Time frame: 240 minutes after beverage consumption
Net Fluid Balance
Net Fluid balance will be calculated subtracting total urine collected from total liquid consumed
Time frame: 0 minutes after beverage consumption
Net Fluid Balance
Net Fluid balance will be calculated subtracting total urine collected from total liquid consumed
Time frame: 60 minutes after beverage consumption
Net Fluid Balance
Net Fluid balance will be calculated subtracting total urine collected from total liquid consumed
Time frame: 120 minutes after beverage consumption
Net Fluid Balance
Net Fluid balance will be calculated subtracting total urine collected from total liquid consumed
Time frame: 180 minutes after beverage consumption
Net Fluid Balance
Net Fluid balance will be calculated subtracting total urine collected from total liquid consumed
Time frame: 240 minutes after beverage consumption
Urine Osmolality
Urine Osmolality will be measured in milliosmoles per kilogram of water.
Time frame: 0 minutes before beverage consumption
Urine Osmolality
Urine Osmolality will be measured in milliosmoles per kilogram of water.
Time frame: 0 minutes after beverage consumption
Urine Osmolality
Urine Osmolality will be measured in milliosmoles per kilogram of water.
Time frame: 60 minutes after beverage consumption
Urine Osmolality
Urine Osmolality will be measured in milliosmoles per kilogram of water.
Time frame: 120 minutes after beverage consumption
Urine Osmolality
Urine Osmolality will be measured in milliosmoles per kilogram of water.
Time frame: 180 minutes after beverage consumption
Urine Osmolality
Urine Osmolality will be measured in milliosmoles per kilogram of water.
Time frame: 240 minutes after beverage consumption
Urine Sodium
Urine Sodium will be measured in millimoles per liter.
Time frame: 0 minutes before beverage consumption
Urine Sodium
Urine Sodium will be measured in millimoles per liter.
Time frame: 0 minutes after beverage consumption
Urine Sodium
Urine Sodium will be measured in millimoles per liter.
Time frame: 60 minutes after beverage consumption
Urine Sodium
Urine Sodium will be measured in millimoles per liter.
Time frame: 120 minutes after beverage consumption
Urine Sodium
Urine Sodium will be measured in millimoles per liter.
Time frame: 180 minutes after beverage consumption
Urine Sodium
Urine Sodium will be measured in millimoles per liter.
Time frame: 240 minutes after beverage consumption
Urine Potassium
Urine Potassium will be measured in millimoles per liter.
Time frame: 0 minutes before beverage consumption
Urine Potassium
Urine Potassium will be measured in millimoles per liter.
Time frame: 0 minutes after beverage consumption
Urine Potassium
Urine Potassium will be measured in millimoles per liter.
Time frame: 60 minutes after beverage consumption
Urine Potassium
Urine Potassium will be measured in millimoles per liter.
Time frame: 120 minutes after beverage consumption
Urine Potassium
Urine Potassium will be measured in millimoles per liter.
Time frame: 180 minutes after beverage consumption
Urine Potassium
Urine Potassium will be measured in millimoles per liter.
Time frame: 240 minutes after beverage consumption
Urine Specific Gravity
Urine Specific Gravity will be measured via refractometry.
Time frame: 150 minutes before beverage consumption
Urine Specific Gravity
Urine Specific Gravity will be measured via refractometry.
Time frame: 0 minutes before beverage consumption urine
Urine Specific Gravity
Urine Specific Gravity will be measured via refractometry.
Time frame: 0 minutes after beverage consumption urine
Urine Specific Gravity
Urine Specific Gravity will be measured via refractometry.
Time frame: 60 minutes after beverage consumption urine
Urine Specific Gravity
Urine Specific Gravity will be measured via refractometry.
Time frame: 120 minutes after beverage consumption urine
Urine Specific Gravity
Urine Specific Gravity will be measured via refractometry.
Time frame: 180 minutes after beverage consumption urine
Urine Specific Gravity
Urine Specific Gravity will be measured via refractometry.
Time frame: 240 minutes after beverage consumption urine
Sodium balance
Sodium Balance will be calculated subtracting total sodium in urine from total sodium consumed in beverage.
Time frame: 0 minutes after beverage consumption
Sodium balance
Sodium Balance will be calculated subtracting total sodium in urine from total sodium consumed in beverage.
Time frame: 60 minutes after beverage consumption
Sodium balance
Sodium Balance will be calculated subtracting total sodium in urine from total sodium consumed in beverage.
Time frame: 120 minutes after beverage consumption
Sodium balance
Sodium Balance will be calculated subtracting total sodium in urine from total sodium consumed in beverage.
Time frame: 180 minutes after beverage consumption
Sodium balance
Sodium Balance will be calculated subtracting total sodium in urine from total sodium consumed in beverage.
Time frame: 240 minutes after beverage consumption
Potassium balance
Potassium Balance will be calculated subtracting total potassium in urine from total potassium consumed in beverage.
Time frame: 0 minutes after beverage consumption
Potassium balance
Potassium Balance will be calculated subtracting total potassium in urine from total potassium consumed in beverage.
Time frame: 60 minutes after beverage consumption
Potassium balance
Potassium Balance will be calculated subtracting total potassium in urine from total potassium consumed in beverage.
Time frame: 120 minutes after beverage consumption
Potassium balance
Potassium Balance will be calculated subtracting total potassium in urine from total potassium consumed in beverage.
Time frame: 180 minutes after beverage consumption
Potassium balance
Potassium Balance will be calculated subtracting total potassium in urine from total potassium consumed in beverage.
Time frame: 240 minutes after beverage consumption
Body Mass
Body Mass in kilograms will be measured using a digital scale
Time frame: 0 minutes before beverage consumption
Body Mass
Body Mass in kilograms will be measured using a digital scale
Time frame: 240 minutes after beverage consumption
Mood and Digestive Questionnaire
Subjects will be asked to self-assess their mood and digestive state via a visual analog scale questionnaire with scale 0 (None) to 10 (Extreme)
Time frame: 0 minutes before beverage consumption
Mood and Digestive Questionnaire
Subjects will be asked to self-assess their mood and digestive state via a visual analog scale questionnaire with scale 0 (None) to 10 (Extreme)
Time frame: 0 minutes after beverage consumption
Mood and Digestive Questionnaire
Subjects will be asked to self-assess their mood and digestive state via a visual analog scale questionnaire with scale 0 (None) to 10 (Extreme)
Time frame: 60 minutes after beverage consumption
Mood and Digestive Questionnaire
Subjects will be asked to self-assess their mood and digestive state via a visual analog scale questionnaire with scale 0 (None) to 10 (Extreme)
Time frame: 120 minutes after beverage consumption
Mood and Digestive Questionnaire
Subjects will be asked to self-assess their mood and digestive state via a visual analog scale questionnaire with scale 0 (None) to 10 (Extreme)
Time frame: 180 minutes after beverage consumption
Mood and Digestive Questionnaire
Subjects will be asked to self-assess their mood and digestive state via a visual analog scale questionnaire with scale 0 (None) to 10 (Extreme)
Time frame: 240 minutes after beverage consumption
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