Asthma, a prevalent chronic condition among children and adolescents, substantially impairs their quality of life. In addressing this significant health concern, this study focuses on the potential of a customized exercise rehabilitation program tailored for this young demographic. By employing a randomized controlled trial design, the research aims to divide participants into two distinct groups: one undergoing a personalized exercise regimen and the other receiving standard medical care. The 12-week intervention for the exercise group includes a combination of aerobic activities, strength training, and targeted breathing exercises. The study's primary aim is to rigorously evaluate the impact of this specialized exercise protocol on critical health aspects such as lung function, physical endurance, frequency of asthma attacks, and overall quality of life. The anticipated findings from this research are expected to shed new light on effective asthma management strategies and offer invaluable guidance for clinical practices dedicated to improving health outcomes in young asthma patients.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
SUPPORTIVE_CARE
Masking
SINGLE
Enrollment
100
The experimental group will participate in a 12-week exercise intervention program, carefully transitioning from moderate-intensity interval training to high-intensity interval training. The progression of exercise intensity will be regularly adjusted based on each child's tolerance, ensuring a personalized approach to the regimen. The exercise program is structured into three phases: an adaptation phase, an intensification phase, and a consolidation phase. For each participant, the intensity of the exercises is calculated based on their reserve heart rate, allowing for a tailored and scientifically-grounded progression. This approach aims to optimize the exercise program's effectiveness while maintaining safety and adaptability to individual fitness levels and asthma conditions.
Lung Function
Forced Vital Capacity (FVC), Forced Expiratory Volume in One Second (FEV1), Forced Expiratory Flow 25% to 75% (FEF25-75), Peak Expiratory Flow (PEF)
Time frame: up to 24 weeks
Daily Physical Activity Level
Daily Step Count (as measured by a pedometer), Energy Expenditure,Time Spent in Moderate-to-Vigorous Intensity Activity
Time frame: up to 24 weeks
Asthma Control Status
asthma control test(ACT)
Time frame: up to 24 weeks
Fractional Exhaled Nitric Oxide (FeNO)
FeNO was determined by NIOX VERO
Time frame: up to 12 weeks
Body Composition
Height, Weight, Body Fat, Skeletal Muscle Content
Time frame: up to 24 weeks
Sleep
Number of Nighttime Awakenings, Sleep Duration
Time frame: up to 24 weeks
Health Related Quality of Life
Asthma Quality of Life Questionnaire
Time frame: up to 24 weeks
Anxiety and Depression
C-C-Ped-PROMIS
Time frame: up to 24 weeks
Inflammatory Mediators
IL-4, IL-5, IL-13
Time frame: up to 12 weeks
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