The goal of this prospective randomized controlled study is to explore the role of indocyanine green-fluorescence imaging in management of cystic lymphatic malformation.. To clarify the application value of indocyanine green-fluorescence imaging in both diagnosis and treatment of cystic lymphatic malformation (cLM) in children, is helpful for exploring pathogenesis of cLM, and providing a clearer scientific basis for subsequent surgical intervention. It also provides alternative for the future diagnosis and treatment of cLM. Participants will receive indocyanine green-fluorescence imaging before operation, while the patients in control group will receive traditional operation. Researchers will compare difference in curative effect between two groups.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Enrollment
110
Inflow occlusion assisted by indocyanine green-fluorescence imaging combined with perforation of septation and sclerotherapy
Perforation of septation and sclerotherapy
Indocyanine green-fluorescence imaging-guided partial resection and sclerotherapy
Partial resection and sclerotherapy
Children's hospital of Nanjing medical university
Nanjing, Jiangsu, China
RECRUITINGCure rate
The percentage of cured cases to total cases
Time frame: 1month, 3 months
Effective rate
The percentage of effective cases to total cases
Time frame: 1 month, 3 months
Treatment frequency
Frequency of treatments
Time frame: 3 months, 6 months
Likert score
Evaluation of postoperative satisfaction
Time frame: 6 months
Wound infection
Infection of surgical region
Time frame: 1 month
Delayed healing
Delayed healing of surgical wound
Time frame: 1 month
Pigmentation
ICG-related pigmentation on skin
Time frame: 1 month
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