Establishment of Human Lung Stem Cell Proliferation System and Organoid Construction in COPD

China-Japan Friendship Hospital30 enrolled

Overview

The goal of this study is to proliferate human lung stem cell in vitro in order to establish a lung organoid derived from patients with COPD. The main question it aims to answer are: * Can human lung stem cell proliferate in vitro. * Can a lung organoid derived from patients with COPD be established. Participants will be sampled during pulmonary bronchoscope for organoid establishment.

Study Type

OBSERVATIONAL

Enrollment

Conditions

Chronic Obstructive Pulmonary Disease

Eligibility

Sex: ALLMin age: 18 YearsMax age: 55 Years

Medical Language ↔ Plain English

Inclusion Criteria: * 1\. Age under 55, regardless of gender * 2\. Patients with COPD lung disease who are going to undergo bronchoscopic biopsy * 3\. No genetic diseases and other respiratory diseases Exclusion Criteria: * Other conditions determined by the investigators to be unsuitable for inclusion, such as difficult sampling, difficult follow-up, and complicated with other serious diseases

Locations (1)

China-Japan Friendship Hospital

Beijing, Beijing Municipality, China

RECRUITING

Outcomes

Primary Outcomes

Number of Patients completed bronchoscope.

Time frame: 1 day

Central Contacts

Mingming Deng, MD

CONTACT

+8618801336854 isdeng1017@163.com

Data from ClinicalTrials.gov

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